The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the …

2024年12月24日 · CRX (Cone-Rod Homeobox) is a Protein Coding gene. Diseases associated with CRX include Cone-Rod Dystrophy 2 and Leber Congenital Amaurosis 7. Among its …

The CRX gene provides instructions for making a protein called the cone-rod homeobox protein. This protein is found in the eyes, specifically in the light-sensitive tissue at the back of the eye …

One of these genes is the cone-rod homeobox (CRX) gene (OMIM: 602225). The CRX gene encodes the 299-aminoacid cone-rod homeodomain protein, which is expressed in the …

2022年7月1日 · Cone-rod homeobox (CRX; OMIM∗602225) is a transcription factor highly expressed in rod and cone photoreceptors, which is essential for their development and …

The Cone-rod homeobox (CRX) protein is a key transcription factor essential for photoreceptor function and survival. Mutations in human CRX gene are linked to a wide spectrum of blinding …

4 天之前 · 1. Introduction. The cone rod homeobox (CRX) gene was first identified and characterized in three independent laboratories as a transcription factor vital for the proper …

The CRX gene provides instructions for making a protein called the cone-rod homeobox protein. This protein is found in the eyes, specifically in the light-sensitive tissue at the

Title: Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model. Downregulation of CRX, a Group 3-specific oncogenic transcription …

One of the isolated cDNAs encoded a novel gene, which the authors termed CRX for 'cone-rod homeobox-containing gene.' CRX encodes a 299-amino acid protein with a predicted mass of …