Chemokine (C-X-C motif) ligand 14 (CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK (for breast and kidney-expressed chemokine). [1] .

CXCL14是趋化因子CXC家族的一个新成员，最早从人类乳腺和肾脏组织中分离克隆而来。 CXCL14参与调控体内许多生物学过程，如炎症免疫反应，肿瘤相关的血管生成，宿主对肿瘤 …

2024年12月24日 · CXCL14 (C-X-C Motif Chemokine Ligand 14) is a Protein Coding gene. Diseases associated with CXCL14 include Cervical Squamous Cell Carcinoma and Squamous …

CXCL14 displays chemotactic activity for monocytes but not for B and T cells. CXCL14 is involved in cancer, immune responses, and epithelial cell proliferation and migration.

2016年1月5日 · CXCL14, a relatively novel chemokine, is a non-ELR (glutamic acid-leucine-arginine) chemokine with a broad spectrum of biological activities. CXCL14 mainly contributes …

Integrative analyses of scRNA-seq and scATAC-seq reveal CXCL14 as a key regulator of lymph node metastasis in breast cancer. Upregulated CXCL14 is associated with poor survival …

2024年1月6日 · Patients with idiopathic pulmonary fibrosis show a strongly upregulated expression of chemokine CXCL14, whose target is still unknown. Screening of CXCL14 in a …

体内试验中肿瘤细胞表达的CXCL14会引起未成熟的树突状细胞 (DC)向肿瘤聚集，在体外实验中，CXCL14能够促使DC的活化。 肿瘤细胞通过下调CXCL14的表达减少DC的聚集从而形成了 …

2024年1月29日 · Therefore, we hypothesized that CXCL14 promotes the development of neurons in the somatic layer of the pyramidal cells of mice cortex on embryonic day 14.5. In order to …

CXCL14 plays important roles in immune surveillance, inflammation and tumor development by regulating cell migration [4]. Previous studies showed that CXCL14 is expressed at high levels …