Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1.

2024年12月24日 · CXCL2 (C-X-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases associated with CXCL2 include Peritonitis and Keratitis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include chemokine activity …

2023年7月1日 · CXC chemokines can recruit and migrate different categories of immune cells, regulate tumor’s pathological behaviors like proliferation, invasion and metastasis, activate angiogenesis, etc....

cxcl2是一种趋化因子，也被称为巨噬细胞炎症蛋白-2。它在细胞和免疫系统中发挥多种作用，包括： 1. 细胞趋化：cxcl2能够吸引和引导免疫细胞（如中性粒细胞、单核细胞和淋巴细胞）向炎症部位或损伤组织移动，参与炎症和免疫反应的调节。

2024年3月1日 · This in-depth study illustrates that the mechanism of Cxcl2+ macrophage-driven neutrophil activation involves the CXCL2-CXCR2 axis and provides a potential therapeutic strategy for age-related liver injury.

2025年3月4日 · Title: CXCL2/10/12/14 are prognostic biomarkers and correlated with immune infiltration in hepatocellular carcinoma. Cis-acting lnc-Cxcl2 restrains neutrophil-mediated lung inflammation by inhibiting epithelial cell CXCL2 expression in virus infection.

炎症归巢作用：炎症趋化因子在感染或损伤过程中产生高浓度，并决定炎症性白细胞向受损区域的迁移。典型的炎性趋化因子包括：ccl2、ccl3和ccl5、cxcl1、cxcl2和cxcl8。一个典型的例子是cxcl-8，它是 中性粒细胞 的趋化剂。与稳态趋化因子受体相比，结合受体和 ...

CXCL2, also called Gro-beta or MIP-2, is a pro-inflammatory cytokine with chemotactic activities on neutrophils. CXCL2 is produced by activated monocytes and neutrophils and expressed at sites of inflammation. CXCL2 is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis. CXCL2 is 90% identical in amino ...

2024年4月18日 · Simultaneously, the enhanced CXCL2-mediated crosstalk between OSCC cells and macrophages plays a vital role in the pro-cancer effect of Fn. Dysbiosis of the oral microbiota is related to chronic...

趋化因子CXC配体2 (CXCL2) 是CXC趋化因子家族中的小分子量细胞因子，也称为巨噬细胞炎症蛋白2 (MIP-2)、细胞因子诱导的中性粒细胞趋化因子3(CINC-3)、生长调节致癌基因β(Gro-β)和Gro致癌基因2(Gro-2)。