
Mechanism of farnesylated CAAX protein processing by the
2013年12月1日 · CAAX proteins have essential roles in multiple signalling pathways, controlling processes such as proliferation, differentiation and carcinogenesis 1.
【修饰篇】异戊烯化修饰蛋白的生物学功能 - 知乎
异戊烯化蛋白调控CAAX蛋白的功能是通过研究FTase抑制RAS蛋白的信号通路过程中发现的。 RCE-1蛋白水解的影响 在小鼠中通过基因干扰手段,发现RCE-1蛋白是唯一可以水解大部分 …
Frontiers | Updates on protein-prenylation and associated …
2024年7月3日 · The C-terminal recognition motif for prenylation is the CAAX (also referred to as Ca 1 a 2 X) domain, in which ‘C’ is the cysteine to be prenylated, ‘A’ is any aliphatic amino …
CAAX-box protein, prenylation process and carcinogenesis
2009年5月25日 · CAAX proteins are widely involved in global cellular functions such as proliferation, differentiation, and carcinogenesis. As an important modulator of biological …
Prenylation of CaaX-type proteins: Basic principles through clinical ...
2002年1月1日 · This chapter deals primarily with the biochemistry and biology of protein prenylation, focusing on those proteins that contain a so-called CaaX motif at their C-terminus. …
Protein phosphatase 2A negatively regulates aPKC signaling by ...
2009年9月15日 · During a mutational screen using the Drosophila compound eye, we identified microtubule star (mts), which encodes a catalytic subunit of protein phosphatase 2A (PP2A), …
Mechanism of farnesylated CAAX protein processing by the ... - PubMed
2013年12月12日 · CAAX proteins have essential roles in multiple signalling pathways, controlling processes such as proliferation, differentiation and carcinogenesis. The ∼120 mammalian …
Cell‐permeable CaaX‐peptides affect K‐Ras downstream signaling …
2020年10月28日 · Cell-permeable peptides bearing a C-terminal CaaX motif based on Ras sequences are introduced. We highlight intracellular accumulation of those peptides, which is …
Cell-permeable CaaX-peptides affect K-Ras downstream signaling …
Herein, we introduce cell-permeable peptides bearing a C-terminal CaaX motif based on Ras sequences. We demonstrate that intracellular accumulation of those peptides in different cells …
CAAX-box protein, prenylation process and carcinogenesis
2009年5月25日 · CAAX proteins are widely involved in global cellular functions such as proliferation, differentiation, and carcinogenesis. As an important modulator of biological …
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