CATH is a classification of protein structures downloaded from the Protein Data Bank. We group protein domains into superfamilies when there is sufficient evidence they have diverged from a common ancestor.

The SCOP database, created by manual inspection and abetted by a battery of automated methods, aims to provide a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known.

CATH 和SCOP 是两个重要的蛋白质结构分类数据库。 CATH 数据库 由伦敦大学1993 年创建。 CATH的名字C、A、T、H 是数据库中四种结构分类层次的首字母。 所有蛋白质结构域在CATH 中被首先分成4 种CLASS，这就是C。 四种CLASS 分别是全α型，全β型， α +β型，低二级结构型。 比如图中第一行这三个蛋白质，很显然左边是全α的，右边是全β的，中间是 α +β的。 每一个Class 中的结构域又被具体分为不同的architecture，也就是A。 A 这一层是按照螺旋和折叠所形成的 …

The CATH Protein Structure Classification database is a free, publicly available online resource that provides information on the evolutionary relationships of protein domains.

2009年4月17日 · We create a new mapping between SCOP and CATH and define a consistent benchmark set which is shown to largely reduce errors made by structure comparison methods such as TM-Align and has useful further applications, e.g. for machine learning methods being trained for protein structure classification.

2022年3月3日 · SCOP（Structural Classification of Proteins）是一个基于蛋白质三维结构的手工分类系统，由研究者通过分析蛋白质结构的相似性和进化关系手动构建。 家族（Family）：基于高序列相似性，将具有相似结构和功能的 蛋白质 放在一起。

Similar to CATH and Pfam databases, SCOP provides a classification of individual structural domains of proteins, rather than a classification of the entire proteins which may include a significant number of different domains. The SCOP database is freely accessible on the internet.

2024年9月21日 · SCOP（Structural Classification of Proteins）是一个基于蛋白质三维结构的手工分类系统，由研究者通过分析蛋白质结构的相似性和进化关系手动构建。 家族（Family）：基于高序列相似性，将具有相似结构和功能的蛋白质放在一起。

cath 和 scop 是两个重要的蛋白质结 构分类数据库。 CATH 数据库( http://www.cathdb.info/ )由伦敦大学 1993 年创建。 CATH 这个数据库的名字 C、A、T、H 是数据库中四种结构分类层次的首字母。

1999年9月15日 · SCOP and CATH both classify the methanol dehydrogenase structure as an eight-bladed propeller fold (CATH indicates this at the architecture level), but disagree on the transducin: CATH classifies it as a six-bladed propeller architecture, whereas SCOP considers it a seven-bladed fold.