CD6 (C luster of D ifferentiation 6) is a human protein encoded by the CD6 gene. [5][6] This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule.

2024年12月24日 · CD6 (CD6 Molecule) is a Protein Coding gene. Diseases associated with CD6 include Multiple Sclerosis and Graft-Versus-Host Disease. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity. An …

Welcome to Los Angeles City Council District 6! The 6th District includes the neighborhoods of Arleta, Lake Balboa, North Hills East, North Hollywood, Panorama City, Sun Valley, Van Nuys. On this site, you can find resources and access constituent services: from bulky item pickup, to concerns about housing and homelessness.

CD6 is a lymphocyte receptor selectively expressed on most T cells and some B cells. CD6 is involved in cell-to-cell contacts and modulation of adaptive immune responses. CD6 interacting partners include CD166/ALCAM, CD318 and certain PAMPS and DAMPS. CD6 is implicated in the pathogenesis of a variety of immune-mediated conditions.

Itolizumab, an anti-CD-6 humanised monoclonal IgG1 antibody, is approved for the management of chronic plaque psoriasis in India. We share our experience of using this drug in three cases of GPP that were failing conventional therapies. Its upstream effect on co-stimulatory pathway in disease pathogenesis is the postulated mechanism.

4 天之前 · CD-6 Caplugs Conduit Fittings & Accessories CD-6 PE-LD01 RED002 MICRO datasheet, inventory, & pricing.

2020年5月1日 · CD6 is a T-cell costimulatory receptor that has been implicated in the pathogenesis of multiple autoimmune and inflammatory diseases. Primarily expressed on CD4 T cells, CD6 promotes immune synapse formation, T-cell activation and T-cell migration via interaction with its ligand activated leukocyte cell adhesion molecule (ALCAM).

CD6是一种关键的1型跨膜糖蛋白，其细胞外部分包含三个富含半胱氨酸的清道夫受体结构域，高度糖基化，并与免疫球蛋白超家族分子CD166（ALCAM）作为其主要配体相互作用。 当CD6与ALCAM结合时，会激活与T细胞活化、增殖、分化和存活相关的丝裂原活化蛋白激酶通路。 这一相互作用在维持免疫平衡、调节T细胞功能及转运中起到重要作用。 研究表明，通过阻断CD6-ALCAM通路，可以抑制致病性T细胞的激活和转运，为相关疾病的治疗提供了新的策略。 此 …

The performance of the resulting player has far exceeded our expectations and is the perfect partner for the highly rated Cyrus 6 amplifier. Whilst the CD6 is a simpler design than the CD8X, it shares many aspects of the CD8X circuit topology.

CD-6 Impeller Features The CD-6 impeller is available in a standard configuration of six concave blades offered in three construction styles: (1) all welded, (2) bolted and (3) adjustable. The adjustable style permits impeller diameter adjustments of ± 6%, which translates to a ± 25% invested power variation. The adjustable construction style ...