CD135 is the receptor for the cytokine Flt3 ligand (FLT3L). It is expressed on the surface of many hematopoietic progenitor cells. Signalling of FLT3 is important for the normal development of …

In this study, we determined the cell-surface expression of the FLT3 receptor (CD135) on the blast population and retrospectively analyzed whether expression was correlated with disease …

The aim of this study was to evaluate the frequencies of CD135 and CD117 expressions in leukemic blast cells, the degree of CD135 and CD117 co-expression (CD135+CD117), and …

The FLT3 receptor (Fms-like tyrosine kinase 3), also known as FLK2 (fetal liver tyrosine kinase 2), STK-1 (stem cell tyrosine kinase 1) or CD135, is encoded by the FLT3 gene located on …

Fms-Like Tyrosine Kinase 3 (Flt3) also known CD135 is the receptor for Flt3-Ligand (Flt3L) that is critical for the development and differentiation of cDC and pDC subsets. cDC1s express higher …

CD135 Antigen In subject area: Medicine and Dentistry The Flt3 receptor is a single transmembrane protein and has an extracellular region composed of five immunoglobulin-like …

2022年8月1日 · In the current study, we identified the CD135 + subset of monocytes as a novel class of APCs in mice. CD135 + monocytes were readily found in the bone marrow, spleen, …

CD135 is an important cell surface marker used to identify certain types of hematopoietic (blood) progenitors in the bone marrow. Specifically, multipotent progenitors (MPP) and common …

CD135 expression ≥ 25% was a predictor of FLT3-ITD mutation (P = .03). CD135 overexpression was a negative predictor of complete remission and of postinduction minimal residual disease …

2019年9月1日 · The aim of this study was to evaluate the CD135 and CD117 expression, co-expression of CD135 and CD117 (CD135+CD117), and the association of that co-expression …