CD24：巨噬细胞检验点的明日之星 2020年11月， 默沙东 宣布以4.25亿美元现金预付款收购OncoImmune的CD24-Fc…
2022年11月12日 · 2020年11月，默沙东宣布以4.25亿美元现金预付款收购OncoImmune的CD24-Fc，这一收购决定是源于CD24-Fc在治疗新冠重症的中期分析中表现出良好的疗效 …
CD24Fc ameliorates immune-related adverse events while
2022年7月15日 · The CD24–Siglec 10/G interaction constitutes an innate checkpoint that regulates inflammation triggered by danger-associated molecular patterns (DAMPs) 2, 3, 4 …
Recombinant Human CD24 Fc Chimera Protein, CF - R&D …
CD24, also known as Heat-Stable Antigen and Nectadrin, is a heavily and variably glycosylated 30 kDa ‑ 60 kDa GPI-linked sialoprotein (1 - 4). Human CD24 is expressed on B lineage cells …
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CD24-Fc resolves inflammation and rescues CD8 T cells with ...
2024年12月16日 · Our findings show that CD24-Fc treatment significantly reduced inflammation and immune hyperactivation in vivo when combined with cART. CD24-Fc mediated resolution …
Novel insights into the function of CD24: A driving force in cancer
2021年2月1日 · In the present review, we summarize recent progress on the role of the CD24-Siglec-10 binding axis at the interface between tumor cells and the immune system, and the …
金斯瑞解读｜肿瘤免疫治疗领域的新秀-CD24 - 百家号
2021年1月13日 · CD24-Fc用于免疫治疗可引起表达siglec10的免疫细胞(T细胞、B细胞、吞噬细胞)的免疫抑制，从而保护自身免疫。在癌症环境中，这可能是有害的。然而，CD24-Fc也可能 …
Novel insights into the function of CD24: A driving force in cancer
2020年8月13日 · In metastatic melanoma, CD24-Fc is being tested for safety and efficacy in combination with the checkpoint inhibitory mAbs ipilimumab and nivolumab, to reduce the …
CD24Fc protects against viral pneumonia in simian ... - Nature
2020年5月7日 · CD24Fc protects SIV-infected Chinese rhesus monkeys from viral pneumonia. a Experimental protocol. The timeline of the study activities is shown at the top. The rhesus …
Insights into CD24 and Exosome Physiology and Potential Role in …
A recombinant fusion protein composed of the extracellular domain of soluble CD24 linked to a human immunoglobulin G1 (IgG1) Fc domain, named CD24Fc, has been identified as a …
CD24-Fc resolves inflammation and rescues CD8 T cells with
2024年12月16日 · Our findings show that CD24-Fc treatment significantly reduced inflammation and immune hyperactivation in vivo when combined with cART. CD24-Fc mediated resolution …