The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3- gamma, - delta and - zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, …

CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T …

2024年12月24日 · CD3E (CD3 Epsilon Subunit Of T-Cell Receptor Complex) is a Protein Coding gene. Diseases associated with CD3E include Immunodeficiency 18 and T-B+ Severe …

2020年8月20日 · Collectively, CD3ε is a built-in multifunctional signal tuner, and increasing CD3 diversity represents a strategy to design next-generation CAR. Keywords: CAR-T therapy; …

2025年3月8日 · Title: Low transcriptomic of PTPRCv1 and CD3E is an independent predictor of mortality in HIV and tuberculosis co-infected patient. Biallelic Form of a Known CD3E Mutation …

2024年4月12日 · An inhibitory ligand acts directly on CD3e to regulate T cell activation, and disruption of the interaction boosts tumor-specific T cell cytotoxicity to limit tumor growth.

CD3E is a prognostic marker in Breast invasive carcinoma, Cervical squamous cell carcinoma and endocervical adenocarcinoma, Head and neck squamous cell carcinoma

2017年4月3日 · In this study we have succeeded in establishing a novel mouse strain in which all the three components of the Cd3 complex — Cd3ε, Cd3δ, and Cd3γ — are replaced by their …

In this study, we examined the role of CD3ε ITAM-mediated signals in T cell development by genetically reconstituting CD3ε-deficient mice with transgenes encoding either wild-type or …

In this study, we established a humanized CD3E mice by replacing the murine Cd3e gene with the human CD3E gene. The humanized CD3E mice can be used as an effective tool for the …