CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120.

The CD4 antibody, clone SK3, is derived from the hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human peripheral blood T lymphocytes. The CD4 antibody recognizes a 55-kilodalton (kDa) glycoprotein that is present on T-helper/inducer lymphocytes and monocytes.

2016年9月28日 · CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of GK1.5 is blocked by RM4-5.

Detects human CD4 in direct ELISAs. Monoclonal Mouse IgG 2A Clone # 11830. Protein A or G purified from hybridoma culture supernatant. Recombinant Human CD4. Supplied in a saline solution containing BSA and Sodium Azide. Phycoerythrin (Excitation= 488 …

PE-65104 targets CD4 in FC applications and shows reactivity with Mouse samples. PBS with 0.1% sodium azide and 0.5% BSA. Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

The reagent CD4 PE permits identification and enumeration of cell populations expressing human CD4 antigen in whole blood using flow cytometry. The reagent contains mouse monoclonal antibody against human CD4 antigen (clone MEM-241) which was purified by affinity chromatography and labeled with R-Phycoerythrin (PE).

The CD4 antibody, clone SK3, is derived from the hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human peripheral blood T lymphocytes. The CD4 antibody recognizes a 55-kilodalton (kDa) glycoprotein that is present on T-helper/inducer lymphocytes and monocytes.

The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations. CD4 is also expressed on thymocyte subsets and at lower levels on monocytes and macrophages.

Human peripheral blood lymphocytes were stained using PE-Texas Red® of anti-human CD4 monoclonal antibody (clone S3.5). The negative control profiles represent unstained cells.