Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a member of the carcinoembryonic antigen (CEA) gene family. [3]

设立分化簇 (CD) 命名系统的目的是对白细胞表面抗原进行分类。 最初，表面抗原是根据与它们结合的对应单克隆抗体进行命名。 随着各实验室逐渐发现抗原常能刺激产生多种单克隆抗体，因此需要采用一种统一的命名系统。 1982 年于巴黎举行的第 1 届国际人类白细胞分化抗原专题讨论会 (HLDA) 上通过了目前使用的命名系统。 根据该命名系统，已经充分表征的抗原将会分配数字（例如，CD1、CD2 等），而对于仅有一种单克隆抗体可以识别的抗原分子，则分配临时名 …

2023年10月31日 · CEACAM5（carcinoembryonicantigen-related cell adhesion molecule-5）又名CD66e或CEA，是癌胚抗原CEA相关细胞粘附分子5（点击查看“什么是CEA家族？ ”）。 CEACAM 5蛋白是CEACAM 5基因的表达产物，具有七条特征性的细胞外Ig链和一个葡萄糖磷脂酰肌醇链，其域结构是N-A1-B1-A2-B2-A3-B3 （图1） [1]。 在CEA基因家族中，研究较多，且与肿瘤发生密切相关的是 CEACAM1 、 CEACAM5 、 CEACAM6 和 CEACAM7。 其中，CEACAM1 …

癌胚抗原（CEA），也被称作癌胚抗原相关细胞粘附分子5、CD66e以及胎粪抗原100（Meconium antigen 100），是免疫球蛋白超家族（IgSF）的成员之一。 CEA借助糖磷脂酰肌醇（GPI）锚定机制固定在细胞膜上；当膜锚定区被磷脂酶C和磷脂酶D裂解时，CEA会进入循环系统。

2022年1月28日 · Recently, the carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) (known as CEA or CD66e) was suggested to be a specific surface protein marker for NEPC. Therefore, we identified a new, fully-human anti -CEACAM5 monoclonal antibody, 1G9, which bound to the most proximal membrane domains, A3 and B3, of …

癌胚抗原(cea) ,也被称为cd66e和ceacam5 ,是一种参与细胞粘附的分子量180-200kd的糖蛋白。 cea通常在胎儿消化系统产生,但由于出生后被抑制,正常成人结肠和血液中cea含量通常很低。然而, cea血清水平升高可由包括结直肠癌、肺癌和乳腺癌在内的多种类型的癌症弓|起。

Description: The monoclonal antibody CB30 recognizes human CD66e, also known as CEA (carcinoembryonic antigen) and CEACAM5. As a member of the immunoglobulin superfamily, it is large GPI-linked glycosylated protein with a molecular weight about 200 kDa.

Invitrogen Anti-CD66e (CEA) Monoclonal (CB30), eBioscience™, Catalog # 14-0669-82. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF), Immunohistochemistry (Paraffin) (IHC (P)) and Flow Cytometry (Flow) applications. This antibody reacts with Human samples. Supplied as 100 µg purified antibody (0.5 mg/mL).

2022年1月28日 · Recently, the carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) (known as CEA or CD66e) was suggested to be a specific surface protein marker for NEPC. Therefore, we identified a new, fully-human anti-CEACAM5 monoclonal antibody, 1G9, which bound to the most proximal membrane domains, A3 and B3, of …

CEA/CD66e (CB30) Mouse mAb detects endogenous levels of CEA protein. Monoclonal antibody (Isotype: IgG1) is produced by immunizing mice with human CEA. Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors.