2022年11月15日 · CD84 antigen is an immunoreceptor member of the SLAM family (SLAMF5), whose expression has been reported in certain immune cells and in B-cell malignancies. In …

2020年9月25日 · In vitro, platelet-derived soluble CD84 enhanced motility of wild-type but not of Cd84-/- CD4 + T cells suggesting homophilic CD84 interactions to drive this process. …

CD84-mediated signaling regulates diverse immunological processes, including T cell cytokine secretion, natural killer cell cytotoxicity, monocyte activation, autophagy, cognate T:B …

2022年11月15日 · With the goal of developing a novel and highly specific CAR-T cell approach for pediatric AML, we performed a large analysis of a gene expression dataset from AML patients …

2021年2月22日 · CD84 is a self-binding immunoreceptor belonging to the signaling lymphocyte activation molecule (SLAM) family. Previously, we showed that CD84 bridges between chronic …

2018年10月2日 · We showed that cell-cell interaction mediated through human and mouse CD84 upregulates PD-L1 expression on CLL cells and in their microenvironment and PD-1 …

2019年7月1日 · CD84 (SLAMF5) is a cell surface receptor expressed on almost all leukocyte subsets. CD84 regulates cytotoxicity, cytokine secretion, autophagy, and T:B interactions. …

2024年11月26日 · Rabani et al. show that CD84 upregulation leads to increased immune suppression in the TME of TNBC. In Bregs, CD84 controls interleukin-10 expression through …

Here, we show that platelet-derived sCD84 acts on CD4 + T-cell CD84 leading to enhanced CD4 + T-cell motility in vitro and aggravated infarct growth following cerebral I/R. Finally, we …

2018年12月3日 · We showed that cell-cell interaction mediated through human and mouse CD84 upregulates PD-L1 expression on CLL cells and in their microenvironment and PD-1 …