
CD96 - Wikipedia
CD96 is a transmembrane glycoprotein that has three extracellular immunoglobulin-like domains and is expressed by all resting human and mouse NK cells. CD96 main ligand is CD155 . CD …
CD96, a new immune checkpoint, correlates with immune profile …
2020年7月1日 · CD96 is a promising candidate for immunotherapy. However, its role and importance in glioma remains unknown. We thus aimed to genetically and clinically …
CD96 Is an Immune Checkpoint That Regulates CD8 - PubMed
CD96 is a novel target for cancer immunotherapy shown to regulate NK cell effector function and metastasis. Here, we demonstrated that blocking CD96 suppressed primary tumor growth in a …
CD96 Gene - GeneCards | TACT Protein | TACT Antibody
2024年12月24日 · CD96 (CD96 Molecule) is a Protein Coding gene. Diseases associated with CD96 include C Syndrome and Developmental And Epileptic Encephalopathy 29. Among its …
CD96 functions as a co-stimulatory receptor to enhance CD8 - PubMed
CD96 was found to transduce its activating signal through the MEK-ERK pathway. CD96-mediated signaling led to increased frequencies of NUR77- and T-bet-expressing CD8 + T …
TIGIT and CD96: new checkpoint receptor targets for cancer ...
2020年3月7日 · A clear understanding of the immune cell populations regulated by TIGIT and CD96 is key to the design of immunotherapies that target these receptors in combination with …
CD96重组蛋白:研究在T细胞活化和免疫调节中的作用
2024年1月19日 · CD96(Cluster of Differentiation 96)是一种细胞表面蛋白,属于Ig超家族的成员之一。 以下是CD96重组蛋白(艾普蒂生物现货目录号:PA1000-6087)的基本信息: 基因 …
药物研发合作新模式丨基因测序新靶点CD96开发取得成功 - 知乎
cd96是制药公司与基因测序公司研发合作模式的一个典型案例,利用基因数据库为药物发现和开发提供新的机会,显示了基因数据库在识别靶标和推进基于人类遗传学新药方面的价值。
CD96 as a Potential Immune Regulator in Cancers - MDPI
2023年1月9日 · Bioinformatics-based analysis of CD96 gene expression in the tissues of patients with hepatocellular carcinoma revealed an increased expression of CD96, suggesting the …
Human CD96 Correlates to Natural Killer Cell Exhaustion and …
Immune checkpoint blockade has become a promising therapeutic approach to reverse immune cell exhaustion. Coinhibitory CD96 and T-cell immunoglobulin and ITIM domain (TIGIT), …