CD97 - Wikipedia
CD97 expression in cancer was first reported for dedifferentiated thyroid carcinoma and their lymph node metastases. [39] CD97 is expressed on many types of tumors including thyroid, …
Science：揭示CD97协助脾脏树突细胞cDC2定位在血流附近对抗病 …
2022年2月20日 · CD97信号使cDC2在组织-血液界面上定位，这个位置可以优化抗原捕获，并能对全身性病原体作出非常快速的免疫反应。 CD97在免疫系统和其他组织（包括一些 肿瘤 和发 …
张岩/孙金鹏/毛春友团队揭示黏附类受体CD97的激活机制
2024年1月15日 · CD97，也被称为ADGRE5，是第一个克隆的人类aGPCR，属于表皮生长因子 (EGF)七跨膜aGPCR家族 (现称为ADGRE家族)。 作为一种原型aGPCR, CD97在N端由3 - 5 …
Structural basis of CD97 activation and G-protein coupling - Cell …
CD97 (ADGRE5) is an adhesion G protein-coupled receptor (aGPCR) which plays crucial roles in immune system and cancer. However, the mechanism of CD97 activation and the determinant …
CD55和CD97：癌症治疗研究新兴靶点 - 知乎 - 知乎专栏
2023年7月13日 · cd55和cd97重组蛋白是免疫学中研究配体相互作用、功能特性和发现潜在治疗靶点的重要工具。 Izuhara及其同事使用人CD55重组蛋白进行实验，以确认其对猫抗CD55抗体 …
Structural characterization of mouse CD97 and study of its specific ...
CD97 is a leucocyte antigen originally recognized on activated human lymphocyte. 1, 2 Activation of lymphocytes by a variety of stimuli rapidly induces the surface expression of CD97. 1, 2 …
CD97 promotes spleen dendritic cell homeostasis through the ...
CD97 signaling allows cDC2s to position at the tissue-blood interface, a location that optimizes antigen capture and enables very rapid immune responses to systemic pathogens.
CD97 maintains tumorigenicity of glioblastoma stem cells via …
2024年12月4日 · Here, we identify cluster of differentiation 97 (CD97) as an optimal GSC surface antigen for potential targeting by chimeric antigen receptor (CAR) T cell therapy through in …
何元政课题组揭示粘附类受体CD97/G蛋白复合物的冷冻电镜结构 …
cd97是最早发现的agpcr，属于表皮生长因子亚家族成员，在体内参与多种免疫反应且与多种自身免疫疾病有关。cd97受体在多种恶性肿瘤中高度表达，曾被用作评估肿瘤恶性程度的指标。该 …
Differential expression of CD97 on human lymphocyte subsets ... - PubMed
2009年4月27日 · CD97 is a large heptahelical EGF-TM7 receptor broadly expressed on hematopoietic cells as three isoforms with respectively three, four, or five epidermal growth …