
Cyclin-dependent kinase 1 - Wikipedia
Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase, and is a key …
CDK(周期蛋白依赖性激酶)_百度百科
激活的 cdk1 可将靶蛋白磷酸化而产生相应的生理效应,如将 核纤层蛋白 磷酸化导致核纤层解体、核膜消失,将 h1磷酸化导致染色体的凝缩等等。这些效应的最终结果使细胞周期不断运行。
CDK1 Gene - GeneCards | CDK1 Protein | CDK1 Antibody
Dec 24, 2024 · CDK1 (Cyclin Dependent Kinase 1) is a Protein Coding gene. Diseases associated with CDK1 include Polyploidy and Retinoblastoma. Among its related pathways are …
周期蛋白依赖性激酶 - 维基百科,自由的百科全书
动物细胞中至少有九种CDK,其中四种Cdk1、2、3、4直接涉及细胞周期的调节 [1] 。在哺乳动物细胞中,CDK1与周期蛋白A2和B1配搭,驱动细胞周期前进 [4] 。而另一个CDK,Cdk7则间 …
细胞周期调控因子-细胞周期蛋白依赖性激酶CDK1 - 知乎
CDK1 (细胞周期蛋白依赖性激酶 1)是一个高度保守的 Ser/Thr 蛋白激酶,在 细胞周期循环中起着重要的作用。 在人体内,Cdk1 是由 CDC2 基因编码,与 cyclin 形成复合物磷酸化一系列的 …
The Cyclin-dependent kinase 1: more than a cell cycle regulator
Oct 28, 2023 · Here, we provide a comprehensive catalogue of the CDK1 upstream regulators and substrates, describing how this kinase is implicated in the control of key ‘cell cycle …
Targeting CDK1 in cancer: mechanisms and implications
Jun 13, 2023 · CDK1 activation plays a critical role in a wide range of cancer types; and CDK1 phosphorylation of its many substrates greatly influences their function in tumorigenesis.
CDK1 cyclin dependent kinase 1 [ (human)] - National Center for ...
Feb 9, 2025 · cyclin-dependent kinase 1 (Cdk1), a known target of E2F1, is involved in G1 checkpoint regulation, as Cdk1 knockdown hindered G1/S progression, while Cdk1 …
CDK1蛋白:细胞周期调控的关键因子 - 哔哩哔哩
Sep 14, 2024 · cdk1是一种关键的细胞周期蛋白依赖性激酶,其主要作用是在有丝分裂期间驱动 细胞周期的进程。 通过与周期蛋白的结合和磷酸化调控,CDK1确保细胞周期的精
CDK1 structures reveal conserved and unique features of the …
Apr 13, 2015 · CDK1 is the only essential cell cycle CDK in human cells and is required for successful completion of M-phase. It is the founding member of the CDK family and is …