Copper is essential for cyclin B1-mediated CDK1 activation
2025年3月7日 · Cyclin-dependent kinase 1 (CDK1) is the pivotal kinase responsible for initiating cell division. Its activation is dependent on binding to regulatory cyclins, such as CCNB1....
CDK1-Specific antibody (19532-1-AP) | Proteintech | 武汉三鹰生 …
19532-1-AP targets CDK1-Specific in WB, IHC, IF/ICC, FC (Intra), IP, ELISA applications and shows reactivity with human, mouse, rat, monkey samples. PBS with 0.02% sodium azide and …
CARM1 S217 phosphorylation by CDK1 in late G2 phase ... - Nature
2025年3月25日 · In late G2 phase, the CDK1/Cyclin B1 complex translocates to the nucleus, where it phosphorylates the S217 residue of CARM1. ... C IP using anti-CARM1 antibody in …
cGAS interacts with CDK1. (A) Co-IP assay to determine the …
... prepositioning CDK1 to chromosome ends where it executes the function. The physical interaction between cGAS and CDK1 was examined by co-IP. The results showed that both …
CDK1-mediated phosphorylation of USP37 regulates SND1
2025年2月18日 · In this study, we focused on understanding the interplay between CDK1, USP37, and SND1 in CRC, proposing a new regulatory mechanism whereby CDK1 …
CDK1 promotes cell proliferation and survival via ... - Nature
2008年4月14日 · Here, we demonstrate that cyclin-dependent kinase 1 (CDK1) specifically phosphorylates FOXO1 at serine 249 (S249) in vitro and in vivo. Coimmunoprecipitation …
Cyclin B1/Cdk1 Coordinates Mitochondrial Respiration for Cell …
Wang et al. find that cyclin B1/Cdk1 localizes to the mitochondrial matrix and phosphorylates complex I to boost mitochondrial respiration and ATP generation during G2/M. Mitochondrial …
The CDK1-TOPBP1-PLK1 axis regulates the Bloom’s syndrome
2022年2月4日 · CDK1 phosphorylates BLM to promote BLM-PLK1 association and also regulates TOPBP1-PLK1 binding, possibly by phosphorylating TOPBP1. By interacting with BLM and …
ACSL4 is phosphorylated by CDK1 at S447. A) Immunoprecipitation (IP …
A) Immunoprecipitation (IP) coupled with immunoblotting (IB) assays using the indicated antibodies testing the effect of CDK1 on ACSL4 phosphorylation. B) Mass spectrometry …
DUX4 Interacts with CDK1 (A) coIP of pCMV-neo-CDK1-HA
Using ReactomePA ( Yu and He, 2016), we identified different cell-cycle regulators, including cyclin-dependent kinase 1 (CDK1), as potential binding partners for DUX4, providing a …