
CDR1as - 百度百科
CDR1as是一种与多种癌症和神经性疾病的发生相关的环状RNA分子。2017年11月,中国科学院水生生物研究所葛峰研究组构建了CDR1as在肝癌细胞中的蛋白调控网络。
【耀文解读】环状RNA(circRNA)的miRNA分子海绵功能与潜在医学 …
关于circRNA的分子海绵作用,研究最为深入的是 CDR1as (小脑变性相关蛋白1的反义转录本),在哺乳动物大脑中广泛存在。研究发现CDR1as存在70多个miR-7保守结合位点,作 …
The circular RNA Cdr1as, via miR-7 and its targets, regulates …
2015年7月27日 · Among the identified thousands of circular RNAs (circRNA) in humans and animals, Cdr1as (also known as CiRS-7) was recently demonstrated to act as a powerful miR …
The Role of Circular RNA CDR1as/ciRS-7 in Regulating Tumor ...
Derived from cerebellar degeneration-related protein 1 antisense transcript (CDR1AS), CDR1as is the best-known circRNA, and has been uncovered as a regulator of cellular processes …
CDR1-AS RNA Gene - GeneCards
2024年12月24日 · CDR1-AS (CDR1 Antisense RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with CDR1-AS include Corneal Dystrophy, Congenital …
环状RNA CDR1as:恶性肿瘤的新型调控因子 - pku.edu.cn
CDR1as是研究最为广泛的circRNA。 它能够通过海绵微RNA(miRNA)或直接结合RNA结合蛋白(RBP),调控其下游基因的表达,激活相关信号通路,从而促进或抑制肿瘤的进展,甚至影响肿瘤 …
The role of CDR1as/ciRS-7 in cardio-cerebrovascular diseases
2023年11月1日 · CDR1as, which was originally discovered in human brain tissues, contains more than 70 conventional binding sites for miR-7; hence, it is also called ciRS-7 [7]. High CDR1as …
CiRS-7/CDR1as; An oncogenic circular RNA as a potential cancer ...
2021年11月1日 · Silencing CDR1as enhances the sensitivity of breast cancer cells to drug resistance by acting as a miR-7 sponge to down-regulate REGγ
环状RNA CDR1as:恶性肿瘤的新型调控因子 - 中国生物化学 ...
CDR1as是研究最为广泛的circRNA。它能够通过海绵微RNA(miRNA)或直接结合RNA结合蛋白(RBP),调控其下游基因的表达,激活相关信号通路,从而促进或抑制肿瘤的进展,甚至影响肿瘤的 …
CDR1as regulates α-synuclein-mediated ischemic brain damage …
CDR1as overexpression significantly suppressed post-stroke α-Syn protein induction, promoted motor function recovery, decreased infarct size, and curtailed the markers of apoptosis, …