DNA replication factor CDT1 - Wikipedia
CDT1 (Chromatin licensing and DNA replication factor 1) is a protein that in humans is encoded by the CDT1 gene. [5] [6] [7] [8] It is a licensing factor that functions to limit DNA from …
CDT1 Gene - GeneCards | CDT1 Protein | CDT1 Antibody
2024年12月24日 · CDT1 (Chromatin Licensing And DNA Replication Factor 1) is a Protein Coding gene. Diseases associated with CDT1 include Meier-Gorlin Syndrome 4 and Meier-Gorlin …
CDT1 chromatin licensing and DNA replication factor 1 [ (human)]
2025年2月8日 · Cdt1 is phosphorylated and its degradation induced by Cdk2 and Cdk4; human CDT1 is essential for DNA replication and chromatin licensing; Cdt1 overexpression …
Cdt1 and geminin in DNA replication initiation - PubMed
One of the mechanisms controlling the initiation of DNA replication is the dynamic interaction between Cdt1, which promotes assembly of the pre-replication license complex, and Geminin, …
Regulation and Function of Cdt1; A Key Factor in Cell ... - PubMed
2016年12月22日 · The Cdc10-dependent transcript 1 protein (Cdt1) is required for the first step in DNA replication, and in human cells Cdt1 is also required during mitosis. Tight cell cycle …
Cdt1 and geminin: role during cell cycle progression and DNA ... - PubMed
2007年1月1日 · Cdt1 is regulated over the course of the cell cycle mainly by the controlled expression of an inhibitor protein, geminin, and the level of Cdt1 periodically fluctuates due to …
染色质许可和 DNA 复制因子 1（CDT1）基因 | MCE
该基因编码的蛋白质参与了 DNA 复制所必需的复制前复合物的形成。 编码的蛋白质可以结合孪蛋白，从而防止复制，并可能起到防止这种蛋白质在不适当的起点开始复制的作用。 细胞周期 …
CDT1, a licensing factor that limits rereplication - Cell Press
2023年1月5日 · Cells must avoid licensing of neosynthesized DNA to prevent rereplication. In this issue of Molecular Cell, Ratnayeke et al. (2022) 1 reveal how the licensing factor CDT1, prior …
Cdt1的调节和功能；细胞增殖和基因组稳定性的关键因素,Genes
2016年12月22日 · DNA 复制的第一步需要依赖 Cdc10 的转录物 1 蛋白 (Cdt1)，在人类细胞中有丝分裂期间也需要 Cdt1。 对 Cdt1 丰度和活性的严格细胞周期控制对于正常发育和基因组稳定 …
CDT1 gene - MedlinePlus
The CDT1 gene provides instructions for making a protein that is important in the copying of a cell's DNA before the cell divides (a process known as DNA replication). Learn about this gene …