Cell-autonomous regulation of complement C3 by factor H limits ...
2023年8月8日 · Complement factor H (CFH) negatively regulates consumption of complement component 3 (C3), thereby restricting complement activation. Genetic variants in CFH …
H因子对补体C3的细胞自主调节限制巨噬细胞胞吞作用并加剧动脉 …
补体因子 h (cfh) 负向调节补体成分 3 (c3) 的消耗，从而限制补体激活。 CFH的基因变异易患慢性炎症性疾病。 在这里，我们研究了 CFH 对动脉粥样硬化发展的影响。
Cell-autonomous regulation of complement C3 by factor H limits …
2023年8月8日 · Complement factor H (CFH) negatively regulates consumption of complement component 3 (C3), thereby restricting complement activation. Genetic variants in CFH …
CFH, C3 and ARMS2 Are Significant Risk Loci for Susceptibility
2009年10月12日 · Variants in the genes encoding complement factor H (CFH), complement component 3 (C3) and age-related maculopathy susceptibility 2 (ARMS2) have repeatedly …
Cell-autonomous regulation of complement C3 by factor H limits ...
Complement factor H (CFH) negatively regulates consumption of complement component 3 (C3), thereby restricting complement activation. Genetic variants in CFH predispose to chronic …
Complement factor H (CFH) negatively regulates consumption of complement component 3 (C3), thereby re-stricting complement activation. Genetic variants in predispose to chronic …
Complement activity is regulated in C3 glomerulopathy by …
C3 glomerulopathy is characterized by accumulation of complement C3 within glomeruli. Causes include, but are not limited to, abnormalities in factor H, the major negative regulator of the …
C3 肾小球疾病的发病机制以及 MPGN 的重新分类 - 搜狐
2020年7月5日 · 在 C3 肾小球疾病的诊断研究中，补体替代途径的主要激活蛋白是 C3 和 CFB，关键调控或抑制蛋白是 CFH、CFI 和 MCP，但五种 H 因子相关蛋白 CFHR1-5 也参与其中（图 …
Complement factor H drives idiopathic pulmonary fibrosis by …
2025年1月1日 · This study identifies CFH as a central regulator in IPF, linking complement dysregulation to macrophage dysfunction and fibrotic progression. CFH promotes fibrosis by …
Factor H uptake regulates intracellular C3 activation during …
2016年1月15日 · Here we report that FH is actively internalized by apoptotic cells to enhance cathepsin L-mediated cleavage of endogenously expressed C3, which results in increased …
- 某些结果已被删除