CFH Y402H polymorphism is associated with elevated vitreal GM …
2015年3月13日 · In this study, we examined vitreal levels of granulocyte macrophage colony-stimulating factor (GM-CSF), a hematopoietic cytokine, and macrophages in the choroid of …
Complement factor H Y402H polymorphism results in diminishing …
2023年11月8日 · Genetic variants in the gene encoding complement factor H (CFH) have been identified as an AMD susceptibility gene, however, the mechanistic link is debated. Here, we …
CFH Y402H polymorphism is associated with elevated vitreal GM …
2015年3月13日 · Our results suggested that the polymorphism in the CFH gene, a known genetic risk factor for AMD, may contribute to the disease process through mechanisms that increase …
CFH Loss in Human RPE Cells Leads to Inflammation and …
We show that loss of the factor H protein (FH) results in increased levels of inflammatory mediators (e.g., IL-6, IL-8, GM-CSF) and altered levels of complement proteins (e.g., C3, CFB …
Complement factor H in AMD: Bridging genetic associations and ...
Genetic studies have strongly supported a relationship between the alternative complement cascade, in particular the common H402 variant in Complement Factor H (CFH) and …
Expression of human complement factor H prevents age-related …
Complement factor H (CFH) is an important regulatory protein in the alternative pathway of the complement system, and CFH polymorphisms increase the genetic risk of age-related macular …
CFH Y402H polymorphism is associated with elevated vitreal GM …
2015年3月13日 · In this study, we examined vitreal levels of granulocyte macrophage colony-stimulating factor (GM-CSF), a hematopoietic cytokine, and macrophages in the choroid of …
(PDF) CFH Y402H SNP Links GM-CSF to AMD Factors
In this study, we examined vitreal levels of granulocyte macrophage colony-stimulating factor (GM-CSF), a hematopoietic cytokine, and macrophages in the choroid of postmortem human …
CFH Variants Affect Structural and Functional Brain Changes
2015年8月5日 · In this study, we performed a genetic screening for AD-related top immune genes identified in Europeans in a Chinese cohort, followed by a multiple-stage study focusing on …
desCripTive sTaTisTiCs and anova resulTs for viTreous Gm-Csf, aGe …
from publication: CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye | Purpose: Age-related macular …