
Cilia-AI
Dysfunctional cilia can lead to nearly 40 severe human genetic syndromes (ciliopathies) with highly heterogeneous, overlapping phenotypes, affecting as many as 1 in 400 people. We now …
The roles of primary cilia in hearing | UCL Ear Institute - UCL ...
Cilia are antenna-like membrane-associated structures which play essential roles during development, and during the normal function of many cells throughout the body. Dysfunction …
Can You Hear Me Now? How The Inner Ear's Sensors Are Made
2008年12月2日 · Located at the ends of cilia -- tiny cellular hairs in the ear that move and transmit signals -- the crystals play an important role in detecting sound, maintaining balance and …
Primary Cilia and Inner Ear Sensory Epithelia | SpringerLink
2012年12月17日 · Primary cilia are essential in sculpturing the hearing organ and the polar hair bundles via the planar cell polarity (PCP) signaling pathway and in controlling …
Cilia in C-Major - Harvard Magazine
Scientists have long known that the eardrum vibrates and transmits the vibration to the inner-ear bones, touching off a mechanical process in the cochlea, the snail-shaped organ containing …
Primary Cilia and Their Role in Acquired Heart Disease - PMC
Primary cilia are non-motile plasma membrane extrusions that display a variety of receptors and mechanosensors. Loss of function results in ciliopathies, which have been strongly linked with …
A change of heart: new roles for cilia in cardiac development and ...
2021年12月3日 · In this Review, we summarize the mechanisms by which cilia contribute to cardiac left–right axis development, identify a role for cilia in congenital heart disease (CHD) …
What Are The Hairs In Your Ears Called? | Fascinating Facts
Ear hairs, or cilia, are tiny structures found in the ear canal. They play a crucial role in maintaining ear health and facilitating hearing. These microscopic hairs are not merely for show; they …
Multiple essential roles for primary cilia in heart development
2012年12月11日 · In the past several years a plethora of papers has indicated a crucial role for primary cilia in the development of a wide variety of organs. We have investigated heart …
Cilia and coordination of signaling networks during heart
2014年1月1日 · Recent studies have indicated a major role of different populations of cilia, including nodal and cardiac primary cilia, in coordinating heart development, and defects in …
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