Hypomethylation of CNTFRα is associated with proliferation and …
2017年8月1日 · Our study demonstrated that hypomethylation leading to CNTFRα up-regulation, together with autocrine expression of CNTF, was involved in glioma growth regulation. …
Ciliary neurotrophic factor has intrinsic and extrinsic roles in ...
2015年10月21日 · Our data reveal that haematopoietic cell-derived CNTF has roles in regulating BM B cell lymphopoiesis and both trabecular and cortical bone, the latter in a sex-dependent …
睫状神经营养因子及受体的研究进展 - 中华康网
睫状神经营养因子（ciliary neurotrophic factor,CNTF）因最初从鸟的睫状神经节中提取出来，可维持副交感神经节活性而得名，它不属于NTFs家族成员，与其无同源性，属非靶源性神经营养 …
转铁蛋白-PEG-睫状神经营养因子的制备及其生物活性评价
2016年4月7日 · 摘要: 为了实现在体内更持久的药效作用,根据睫状神经营养因子CNTF第17位为游离半胱氨酸残基,而转铁蛋白Tf无游离半胱氨酸的特点,采用N-羟基琥珀酰亚胺-聚乙二醇5K-马 …
睫状神经营养因子 (CNTF)是什么？ - 知乎
CNTF是一种多能性神经细胞因子，是一种潜在的抗肥胖治疗方法。 CNTF在中枢和外周发挥作用，在克服“瘦素抵抗”的同时模仿瘦素的生物学作用，即使在终止治疗后，如果集中给药，它仍 …
Survey Ciliary neurotrophic factor (CNTF): New facets of an old ...
2015年10月1日 · New receptor specific CNTF variants represent promising therapeutic agents for obesity and metabolic diseases. CNTF-producing cells are being currently evaluated for …
Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRɑ) signal ...
Ciliary neurotrophic factor (CNTF) is a member of interleukin-6 type cytokine family. The CNTF receptor complex is a heterodimer including gp130 and CNTF receptor α (CNTFRɑ) proteins …
CNTF, a pleiotropic cytokine: emphasis on its myotrophic role
2004年12月1日 · Ciliary neurotrophic factor (CNTF) is a cytokine whose neurotrophic and differentiating effects over cells in the central nervous system (CNS) have been clearly …
睫状神经营养因子 (CNTF) | 重组蛋白 | MCE - MCE-生物活性 ...
CNTF 显示出与 IL-6 受体亚基-α (IL-6Rα) 的低亲和力相互作用，可导致 IL-6Rβ/gp130/LIFR 信号受体复合物的形成和激活 [1]。 CNTF 也是神经视网膜和光感受器基质中的细胞外信号蛋白，与 …
Ciliary Neurotrophic Factor (CNTF) and Its Receptors Signal …
Ciliary neurotrophic factor (CNTF) was identified as a survival factor in various types of peripheral and central neurons, glia and non-neural cells. At present, there is no available data on the …