
Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRɑ) signal ...
Ciliary neurotrophic factor (CNTF) is a member of interleukin-6 type cytokine family. The CNTF receptor complex is a heterodimer including gp130 and CNTF receptor α (CNTFRɑ) proteins …
Ciliary neurotrophic factor - Wikipedia
Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. [5] [6] [7] The protein encoded by this gene is a polypeptide hormone and neurotrophic factor whose actions …
《CNTF联合RA诱导成肌细胞类神经分化及与REST的相关性研究》.…
2025年1月15日 · 本研究表明,CNTF联合RA可以诱导成肌细胞实现类神经分化,这为研究神经肌肉系统的交互作用提供了新的思路和方法。 同时,研究发现REST在成肌细胞类神经分化过程 …
Single particle electron microscopic analysis of the full-length gp130/LIF-R/CNTF-Ra/ CNTF quaternary complex elucidates an asymmetric structural arrangement, in which the receptor …
Survey Ciliary neurotrophic factor (CNTF): New facets of an old ...
2015年10月1日 · CNTF-producing cells are being currently evaluated for treatment of retinal degeneration for fast-track approval by the FDA. Ciliary neurotrophic factor (CNTF) is the most …
Ciliary neurotrophic factor-mediated neuroprotection involves
2022年11月17日 · Rhee et al. demonstrates that the potent neuroprotective agent CNTF significantly impacts metabolism of degenerating retinas, thus revealing cellular mechanisms …
Neuroprotective properties of ciliary neurotrophic factor on …
Ciliary neurotrophic factor (CNTF) is a neurocytokine, which could promote survival and/or differentiation in many cell types. In this study, the biological effects of CNTF on retinoic acid …
睫状神经营养因子 (CNTF)是什么? - 知乎
CNTF是神经元和少突胶质细胞的有效生存因子,它可能与减少炎症性发作期间组织破坏有关。 中枢神经系统外,CNTF的主要靶组织之一是骨骼肌。 目前已经证明CNTF还可以在骨表面细胞 …
CNTF 联合RA 诱导成肌细胞类神经分化及与REST 的相关性
方法 以cntf 诱导c2c12 去分化,再以ra 诱导 c2c12 类神经分化。 通过细胞形态学、细胞免疫荧光、流式细胞术、Western blot 等技术对去分化及类神经 分化的细胞进行鉴定及相关分析,比较 …
《CNTF联合RA诱导成肌细胞类神经分化及与REST的相关性研究》
2025年1月10日 · 1.cntf联合ra诱导成肌细胞类神经分化. 实验结果显示,在cntf和ra的联合作用下,成肌细胞的形态逐渐发生变化,呈现出神经细胞的特征。同时,实时荧光定量pcr结果显 …