The Children's Oncology Group's A5971 trial examined central nervous system (CNS) prophylaxis and early intensification in paediatric patients diagnosed with CNS-negative Stage III and IV lymphoblastic lymphoma. Using a 2 × 2 factorial design, the study randomized patients to Children's Cancer Group …

2012年12月15日 · We report the 5-year event-free survival (EFS) and overall survival (OS) for children and adolescents with localized LL treated on a uniform regimen based on Children's Cancer Group (CCG) leukemia therapy (COG A5971). Procedure: From June 2000 to October 2005, the study enrolled 60 patients >12 months old with Murphy stages I or II LL. Central ...

2023年3月1日 · Analysis of 180 patients with T-LBL enrolled in the Children's Oncology Group (COG) trial A5971 showed a similar immunophenotype to T-ALL samples except for a higher incidence of CD4/CD8 double positivity, indicating a more mature stage of differentiation [16].

2013年7月24日 · The Children's Oncology Group's A5971 trial examined central nervous system (CNS) prophylaxis and early intensification in paediatric patients diagnosed with CNS‐negative Stage III and IV lymphoblastic lymphoma.

The recent COG A5971 trial for LL used various diagnostic imaging modalities, including CT, gallium, and PET scanning, at several time points during induction therapy to determine whether early tumor response is related to treatment outcome .

2013年7月24日 · The Children's Oncology Group's A5971 trial examined central nervous system (CNS) prophylaxis and early intensification in paediatric patients diagnosed with CNS‐negative Stage III and IV lymphoblastic lymphoma.

2008年11月16日 · High-Dose Methotrexate and Early Intensification of Therapy Do Not Improve 3 Year EFS in Children and Adolescents with Disseminated Lymphoblastic Lymphoma. Results of the Randomized Arms of COG A5971. Blood (2008) 112 (11): 3610.

The Children's Oncology Group's A5971 trial examined central nervous system (CNS) prophylaxis and early intensification in paediatric patients diagnosed with CNS-negative Stage III and IV...

我们报告了基于儿童癌症组 (ccg) 白血病治疗 (cog a5971) 的统一方案治疗的局限性 ll 儿童和青少年的 5 年无事件生存率 (efs) 和总生存率 (os)。 程序 从 2000 年 6 月到 2005 年 10 月，该研究招募了 60 名 >12 个月大的墨菲 I 或 II 期 LL 患者。

2012年12月12日 · The Children’s Oncology Group (COG) trial A5971 enrolled patients from 2000 to 2005 and included all newly diagnosed patients with lymphoblastic lymphoma. Patients with Murphy stage I and II were non-randomly assigned therapy on a modified Children’s Cancer Study Group (CCG BFM) acute lymphoblastic leukemia regimen, as previously described ...