2000年10月27日 · This manuscript demonstrates that: (1) CPEB and maskin are microtubule binding proteins that are found on the spindles and centrosomes of animal pole blastomeres, …

2022年9月12日 · Based on a comparative analysis of the four vertebrate CPEBs, we determine their differential regulation by phosphorylation, the composition and properties of their …

CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine tail of messenger RNA. [1] CPEB is …

2001年7月15日 · In this study, we have examined the phosphorylation of CPEB and have assessed the necessity of this protein for polyadenylation in maturing mouse oocytes.

In the nervous system, the CPEB proteins are involved in cell division, neural development, learning, and memory. Here we consider the functional features of these proteins in the …

2023年5月2日 · Biochemical analysis of the vertebrate CPEBs demonstrate them to respond to different signaling pathways whose output leads to specific cellular responses. In addition, the …

2000年10月27日 · Results indicate that the cytoplasmic polyadenylation element (CPE) within the 3’UTR of Aurora B, a recognition sequence of CPEB, is essential for RNA localization to the …

2022年2月17日 · We demonstrate phosphorylation-dependent CPEB1 promoted Myod1 protein synthesis by binding to the cytoplasmic polyadenylation elements (CPEs) within its 3′ UTRs to …

2000年11月1日 · CPEB and maskin, two factors that control polyadenylation-induced translation are present on the mitotic apparatus of animal pole blastomeres in embryos. Cyclin B1 protein …

Cyclin-B mRNAs contain one such element called the cytoplasmic polyadenylation element (CPE) responsible for recruiting the cytoplasmic polyadenylation element-binding protein (CPEB), …