CRBN (D8H3S) Rabbit mAb | Cell Signaling Technology
4 天之前 · CRBN (D8H3S) Rabbit mAb recognizes endogenous levels of total CRBN protein. Human, Mouse, Rat. Monoclonal antibody is produced by immunizing animals with a synthetic …
Anti-CRBN antibody [4D6] Mouse monoclonal (ab244223) - Abcam
Knockout Tested Mouse Monoclonal CRBN antibody. Suitable for IHC-P, WB and reacts with Human, Mouse samples. The exact immunogen used to generate this antibody is proprietary …
- 评论数: 1
Molecular glue CELMoD compounds are regulators of cereblon
2022年11月3日 · CRBN is a 50-kDa protein containing three folded domains: an N-terminal Lon protease-like domain (hereafter, Lon domain), an intermedial helical bundle (HB), and a C …
CRBN antibody (11435-1-AP) | Proteintech - ptglab
We tested CBRN antibody in mouse heart and brain tissue extracts. CRBN antibody have specificity to recognize CRBN by western blot which was confirmed by knockout mice. …
- 评论数: 6
Anti-CRBN抗体[4D6] (ab244223) - Abcam中文官网
In Western blot, ab244223 was shown to bind specifically to CRBN. A band was observed at 51 kDa in wild-type cell lysates with no signal observed at this size in CRBN knockout cell lines.
- 评论数: 1
Science | 靶向蛋白降解途径突破，几乎可用于任何疾病相关蛋白
2022年11月22日 · CRBN （cereblon）是CRL4CRBN E3连接酶复合物的底物识别亚单位。 Scripps Research的科学家们发现了一种有前途的新型抗癌药物 CELMoDs 的一个关键特性。 …
An engineered cereblon optimized for high-throughput screening …
2025年2月20日 · CRBN_ΔHBD has equivalent activity to CRBN:DDB1 toward thalidomide-based tool compounds, unlike previous E. coli-expressed CRBN constructs. Future use of …
CRBN (D8H3S) Rabbit mAb (BSA and Azide Free) #46351
CRBN (D8H3S) Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total CRBN protein. Human, Mouse, Rat. Monoclonal antibody is produced by immunizing animals with a …
重组Anti-CRBN抗体[EPR28739-64] (ab315344) - Abcam中文官网
The molecular weight observed around 100 kDa is autoubiquitination of CRBN, which is consistent with what has been described in the literature (PMID: 25043012). Lanes 1-3 are …
CRBN- 信号通路|蛋白抗体-华美生物
CRBN作为底物识别亚单位，通过与DDB1、Cul4A、ROC1形成E3泛素连接酶复合物，促进目标蛋白质的泛素化和随后的蛋白酶体降解，如MEIS2或ILF2。 CRBN维持突触谷氨酸释放，对认知 …
- 某些结果已被删除