CREB-binding protein, also known as CREBBP or CBP or KAT3A, (where CREB is cAMP response element-binding protein) is a coactivator encoded by the CREBBP gene in humans, …

2024年12月24日 · First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic …

CREB-binding protein (CREBBP) and E1A-binding protein P300 (EP300) are two key acetyltransferases and transcriptional cofactors that regulate gene expression by regulating …

The CREBBP gene provides instructions for making CREB binding protein, which regulates the activity of many genes in tissues throughout the body. Learn about this gene and related …

2025年2月9日 · First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, …

2024年5月1日 · Targeting EP300/CREBBP holds great promise for treating leukemia with some certain cytogenetic abnormalities. Here, we demonstrated that EP300 and CREBBP are core …

Chrivia et al. (1993) reported the discovery of a nuclear transcriptional coactivator protein, CREB-binding protein (CBP), that binds specifically to the PKA-phosphorylated form of the CREB …

First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and …

2024年7月7日 · First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, …

CREB binding protein (CREBBP) is a gene that encodes a protein that functions in transcriptional activation and is involved in the regulation of embryonic development, growth control, and …