Kolliphor EL, formerly known as Cremophor EL, is the registered trademark of BASF Corp. for its version of polyethoxylated castor oil. It is prepared by reacting 35 moles of ethylene oxide with each mole of castor oil.

Cremophor EL-40 是一种聚氧乙烯蓖麻油衍生物，是一种非离子表面活性剂。 Cremophor EL-40 被广泛用于改善活性分子的溶解和输送。

Cremophor is a non-ionic solubilizer and emulsifier that is made by reacting ethylene oxide with castor oil (1). It is a pale yellow oily liquid consisting of a mixture of components, primarily polyethylene glycol conjugates.

Cremophor EL (CrEL) is a formulation vehicle used for various poorly-water soluble drugs, including the anticancer agent paclitaxel (Taxol). In contrast to earlier reports, CrEL is not an inert vehicle, but exerts a range of biological effects, some of which have important clinical implications.

Cremophor® RH 40 is a nonionic multipurpose solubilizer and emulsifying agent that is used to solubilize ethereal oils, perfume compositions, vitamins, and hydrophobic active substances in aqueous-alcoholic and purely aqueous solutions.

Hypersensitivity reactions to Cremophor EL-containing paclitaxel range from mild pruritus to systemic anaphylaxis and can result in potentially severe clinical outcomes, including respiratory arrest, cardiac collapse, and death. 1 In Cremophor EL-containing paclitaxel clinical trials, up to 41% of patients experienced a hypersensitivity reaction.

Cremophor® RH 40 is used to solubilise ethereal oils, perfume compositions, vitamins and hydrophobic active substances in aqueous- alcoholic and purely aqueous solutions.

2021年10月14日 · Cremophor EL | C5H12O4 | CID 104840 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Cremophor系列增溶剂常被用于化妆品产业中。 Cremophor RH40几乎无色无味，含有极少量的芳烃。 适用于脂溶性的维他命，矿物油以及其他非水溶性的化妆品组分。 Cremophor EL由蓖麻油乙氧基化生成，HLB值为12-14。 并且可溶于水、乙醇、氯仿、蓖麻油、橄榄油、脂肪酸、脂肪醇中。