We have defined a new paraneoplastic immunoglobulin G (IgG) autoantibody specific for CRMP-5, a previously unknown 62-kd neuronal cytoplasmic protein of the collapsin response …

Collapsin response mediator protein family or CRMP family consists of five intracellular phosphoproteins (CRMP-1, CRMP-2, CRMP-3, CRMP-4, CRMP-5) of similar molecular size …

We found that peripheral neuropathy and cerebellar ataxia together with lung cancer were the most common diagnoses associated with CRMP5 antibodies. CRMP5-CBA was easy to …

2017年12月8日 · To establish the phenotype and clinical outcomes of collapsin response-mediator protein-5 (CRMP5) autoimmune neuropathy in comparison with anti-neuronal nuclear …

CV2抗体可特异性识别坍塌反应调节蛋白（collapsing response mediator proteins，CRMPs），包括5个高度同源的胞质蛋白（CRMP1-5）， 其中最常识别的是CRMP-5。 CRMP-5可在小细胞 …

2015年12月9日 · CRMP family proteins (CRMPs) are abundantly expressed in the developing nervous system mediating growth cone guidance, neuronal polarity and axon elongation. …

Anti‐CV2/CRMP‐5‐IgG is a neuronal autoantibody most commonly associated with small cell lung cancer. 1 The associated paraneoplastic syndrome can include chorea (11% of patients), …

Collapsin response mediator protein 5-associated optic neuropathy (CRMP5-ON) is a rare entity of autoimmune optic neuropathy. This study aimed to review the neuro-ophthalmic findings …

近日研究人员对Collapsin反应调节蛋白5（CRMP5）自身免疫性神经病变的表型与临床特征进行了考察，比较其与抗神经元核抗体1型(ANNA1)G免疫球蛋白神经病变的差异。

2018年1月9日 · Conclusion: Painful axonal asymmetric polyradiculoneuropathy is established as the major CRMP5 autoimmune neuropathy presentation and is distinguishable from other …