DNA Sequence Recognition of Human CXXC Domains and Their …
2018年1月2日 · The CXXC domain, first identified as the reader of unmodified CpG dinucleotide, plays important roles in epigenetic regulation by targeting various activities to CpG islands. …
DNA Sequence Recognition of Human CXXC Domains and Their …
2018年1月2日 · Through a series of crystal structures of CXXC domains with DNA ligands, we unravel the molecular mechanisms of how these CXXC domains, including single CXXC …
CXXC1 - Wikipedia
CpG-binding protein (CGBP) also known as CXXC-type zinc finger protein 1 (CXXC1) or PHD finger and CXXC domain-containing protein 1 (PCCX1) is a protein that in humans is encoded …
Cxxc finger protein 1 maintains homeostasis and function of …
2023年7月10日 · CXXC finger protein 1 (Cfp1, encoded by the Cxxc1 gene) is a conserved subunit of the SET1 H3K4 methyltransferase, which, in complex with Setd1b, binds to DNA via …
CXXC finger protein 1 (CFP1) bridges the reshaping of genomic
2023年9月21日 · We have unveiled that CFP1 promote lung adenocarcinoma (LUAD) cell proliferation, migration, and invasion while impairing cell apoptosis through in vitro and in vivo …
CXXC5 as an unmethylated CpG dinucleotide binding protein
2020年4月6日 · Evidence suggests that the CXXC type zinc finger (ZF-CXXC) protein 5 (CXXC5) is a critical regulator/integrator of various signaling pathways that include the estrogen (E2) …
Structural Basis for the Recognition of Non-methylated DNA by the CXXC ...
2020年3月13日 · The CXXC deletion of FBXL19 displays growth retardation and impaired embryonic development, and finally leads to embryonic lethality in mice, suggesting that CXXC …
80319 - Gene ResultCXXC4 CXXC finger protein 4 [ (human)]
2025年2月8日 · CXXC4 is a novel potential tumor suppressor directly regulated by EZH2, and its expression is a significant prognosis factor for patients with early stages of gastric cancer. …
30827 - Gene ResultCXXC1 CXXC finger protein 1 [ (human)]
2025年2月9日 · This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a …
Identity and functions of CxxC-derived motifs - PubMed
2003年9月30日 · A search for conserved CxxC-derived motif/helix patterns in four complete genomes representing bacteria, archaea, and eukaryotes identified known redox proteins and …