DBCO-PEG4-VC-PAB-MMAE 可用于合成抗体-活性分子偶联物 (ADCs)。MMAE 是 dolastatin10 的合成衍生物，通过抑制微管蛋白聚合作用，作为一种有效的有丝分裂抑制剂。DBCO-PEG4-VC-PAB-MMAE 是一种点击化学试剂。

Dibenzocyclooctyne-amine (DBCO-NH2), is a heterobifunctional linker containing a DBCO moiety commonly used for the site-specific functionalization of nanobodies, enabling the addition of reactive DBCO groups for subsequent click chemistry reactions.

中文名:氮杂二苯并环辛炔胺,英文名:Azadibenzocylooctyne-amine,CAS:1255942-06-3,化学式:C18H16N2O,分子量:276.3324,密度:1.25±0.1 g/cm3 (Predicted),熔点:86-96°C,沸点:549.9±50.0 °C (Predicted),MSDS.

11,12-Didehydro-gamma-oxodibenz [b,f]azocine-5 (6H)-butanoic acid | C19H15NO3 | CID 91757805 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2025年1月27日 · DBCO-amine is an aza-dibenzocyclooctyne (DBCO) product used for strain-promoted azide-alkyne cycloaddition (SPAAC, also known as “copper-free click chemistry”). The DBCO moiety reacts selectively with azides via SPAAC to form stable triazole linkages.

二苯并环辛炔胺（DBCO-NH2） 是一种杂官能团连接剂，含有一个DBCO结构单元，该结构单元常用于纳米抗体（nanobodies ）的位点特异性官能化，促进随后的点击化学反应中反应 …

2024年12月18日 · DBCO-acid的反应原理主要基于其DBCO基团与含有叠氮基团的化合物之间发生的无铜点击化学反应，也称为叠氮-炔烃环加成反应（SPAAC）。 这种反应类型以其高效性和选择性著称，能够在无需催化剂的情况下进行。

DBCO Acid is a bifunctional building block comprising of an acid terminus useful for reaction with amine containing linkers in presence of activators such as EDC or HATU and a dibenzocyclooctyne (DBCO) terminus useful for copper-free click chemistry.

CAS Number: 1255942-08-5. Molecular Weight: 523.62 (free base basis) MDL number: MFCD28334576. UNSPSC Code: 12352200. ... DBCO-PEG4-Amine TFA is a heterobifunctional building block with two reactive terminals. The Dibenzocyclooctyne (DBCO) terminus is useful for copper-free click chemistry. DBCO compounds react with azides without need of Cu(I ...

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