DC-SIGN is a C-type lectin receptor present on the surface of both macrophages and dendritic cells. DC-SIGN on macrophages recognises and binds with high affinity to high-mannose type …

DC-SIGN全称是树突状细胞特异性细胞间粘附分子-3-结合非整合素分子(dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintergrin,DC-SIGN),又称CD209,表达在未成熟 …

DC-SIGN is a prototype C-type lectin organized in microdomains, which have their role as pathogen recognition receptors in sensing microbes. Although the integrin LFA-1 is a counter …

2003年9月1日 · Cell- and tissue-specific glycosylation of a glycoprotein regulates the expression of carbohydrate residues and recognition by specific C-type lectins. The C-type lectin DC …

2000年3月3日 · A new DC-restricted molecule, DC-SIGN, demystifies two of this cell's contrasting functions: stimulating T lymphocytes to develop immunity, and enhancing HIV-1 and SIV …

DC-SIGN, which is expressed by dendritic cells, binds to ICAM-3 on T-lymphocytes, therefore playing an important role in the activation of T-lymphocytes. DC-SIGN can also bind HIV, and …

Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) is a type II transmembrane lectin receptor. Attention on DC-SIGN has increased greatly in recent years …

DC-SIGN is a prototype type II transmembrane protein consisting of a carboxy- (COOH-) terminal carbohydrate recognition domain (CRD), followed by a neck domain consisting of one …

dc-sign作为dc表面上的一种受体，在体内发挥着重要作用。 DC-SIGN可以与主要表达于血管和淋巴管内皮细胞上的细胞间黏附分子-2（intercellular adhesion molecule-2，ICAM-2）相互作 …

2000年3月3日 · DC-SIGN, which is abundantly expressed by DC both in vitro and in vivo, mediates transient adhesion with T cells. Since antibodies against DC-SIGN inhibit DC …