5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine), also known as O-methylbufotenin or mebufotenin (INN), is a naturally occurring psychedelic of the tryptamine family. [5][1][4][2] It is found in a wide variety of plant species, and is also secreted by the glands of at least one toad species, the Colorado River toad. [5] .

2024年9月10日 · DMT (Dimethyltryptamine) is one of the most potent naturally occurring psychedelics known to science. While there are several variations of this compound, the two most prominent forms are N,N-DMT and 5-MeO-DMT. Both substances are powerful and can lead to profound, often life-changing experiences, but they offer distinctly different effects and ...

2025年1月15日 · 5-MeO-DMT (N,N-Dimethyl-5-methoxytryptamine) is a psychedelic tryptamine, 4 – 6 times stronger than the better-known DMT (N,N-dimethyltryptamine).

2016年2月26日 · DMT, in the form of a long-lasting ayahuasca experience, may help those attempting to open themselves up, to travel outward to bring back insights. 5-MeO-DMT, on the other hand, has its place as a very brief but effective supplement to an ibogaine experience as a way to become one with the universe.

2025年3月12日 · DMT and 5-MeO-DMT are both powerful psychedelics with distinct effects and mechanisms of action. DMT produces vivid visual hallucinations, while 5-MeO-DMT induces an immersive, ego-dissolving state. These differences have drawn interest from neuroscientists, psychonauts, and clinicians exploring their therapeutic potential.

6-MeO-DMT, or 6-methoxy-N,N-dimethyltryptamine, also known as 6-OMe-DMT, is a serotonergic drug of the tryptamine family. [1] [2] It is the 6-methoxy derivative of the serotonergic psychedelic N,N-dimethyltryptamine (DMT) and is a positional isomer of the serotonergic psychedelic 5 …

2024年8月3日 · Structurally similar to the more well-known DMT (N,N-dimethyltryptamine), 5-MeO-DMT is renowned for its intense, short-lasting psychedelic effects. It acts as a powerful serotonin receptor agonist, primarily affecting the 5-HT2A receptor, which plays a crucial role in modulating mood, perception, and cognition.

2023年12月11日 · 5-MeO-DMT is a tryptamine being developed as a potential antidepressant that may display a distinct therapeutic mechanism due to its unique pharmacology and subjective effects compared to typical psychedelics. In this article, we parallel the relatively distinct phenomenology and behavioral effects …

There is particular interest in 5-methoxy- N,N -dimethyltryptamine (5-MeO-DMT)—a serotonergic psychedelic—as a novel, fast-acting therapeutic. Yet, few studies have directly examined 5-MeO-DMT for trauma- or stress-related psychopathology, …

Basics: 5-MeO-DMT is short for 5-methoxy-N,N-dimethyltryptamine. It’s found in several plants and in high concentrations in the secretion of the toad Bufo alvarius. It’s also possibly produced by the human body and has been found in human blood, urine, and cerebrospinal fluid. It’s usually inhaled through vaporizing or snorting.