2010年2月5日 · AtTRB1, 2 and 3 are members of the SMH (single Myb histone) protein family, which comprises double-stranded DNA-binding proteins that are specific to higher plants. They are structurally conserved, containing a Myb domain at the N-terminus, a central H1/H5-like domain and a C-terminally located coiled-coil domain.

Here, we describe the discovery and characterization of the maize Single myb histone 1 (Smh1) gene encoding a DNA-binding protein capable of binding maize telomere repeat sequences in vitro.

2003年11月11日 · The Maize Single myb histone 1 Gene, Smh1, Belongs to a Novel Gene Family and Encodes a Protein That Binds Telomere DNA Repeats in Vitro. We screened maize (Zea mays) cDNAs for sequences similar to the single myb-like DNA-binding domain of known telomeric complex proteins.

We analyze the DNA-protein interaction of the full-length and truncated variants of AtTRB1, a SMH-family member with a typical structure: N-terminal Myb domain, central H1/5 domain and C-terminal coiled-coil.

2003年12月1日 · The Smh1 gene encodes a small, basic protein with a unique triple motif structure of (a) an N-terminal SANT/myb-like domain of the homeodomain-like superfamily of 3-helical-bundle-fold proteins,...

Early Neolithic individuals from Stuttgart-Mühlhausen (SMH), Schwetzingen (SCH), and Halberstadt (HBS) in Germany [44 published and 42 newly reported, of which 5 low-coverage individuals (<18,000 SNPs mapping on the HO panel) are shifted toward the centroid] representing the LBK horizon (17 sites from Hungary, Austria, and Germany) form a ...

2009年3月13日 · Proteins that bind telomeric DNA modulate the structure of chromosome ends and control telomere function and maintenance. It has been shown that AtTRB (Arabidopsis thaliana telomere-repeat-binding factor) proteins from the SMH (single-Myb-histone) family selectively bind double-stranded telomeric DNA and interact with the telomeric protein ...

2019年3月7日 · 研究人员通过基因敲除实验发现，dna正是依赖cgas和sting刺激细胞自噬的发生！ 在固有免疫中，STING 是诱导干扰素功能的关键，决定了干扰素的生成。 研究人员将细胞的TANK结合激酶1（TBK1）敲除或对细胞使用TBK1抑制剂后，发现使用cGAMP不能激活干扰素调 …

We screened maize (Zea mays) cDNAs for sequences similar to the single myb-like DNA-binding domain of known telomeric complex proteins. We identified, cloned, and sequenced five full-length cDNAs representing a novel gene family, and we describe the

The labeled ds oligonucleotide probe, WT-4R [5 Ј -GGATAC(TTTAGGG) 4 CGAGTC-3 Ј plus its complementary C-rich strand], was observed as free probe from publication: The Maize Single myb histone 1 ...