2023年5月1日 · To interrogate the downstream effectors of DRD2 signaling in GBM, we took two independent but complementary approaches: (1) co-immunoprecipitation (IP)-mass spectrometry (MS) to characterize the proteins that interact with DRD2 and (2) phosphorylated protein profiling assays to determine the effector molecules that are modulated by dopamine ...

55084-1-AP targets DRD2 in WB, IHC, IF-P, IP, ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. DRD2, also named D2DR and D2R, belongs to the G-protein coupled receptor 1 family.

2020年2月26日 · Here, we report the crystal structure of DRD2 bound to the most commonly used antipsychotic drug, haloperidol. The structures suggest an extended binding pocket for DRD2 that distinguishes it...

2020年6月11日 · DRD2 is activated by the endogenous neurotransmitter dopamine and synthetic agonist drugs such as bromocriptine 3, leading to stimulation of G i and inhibition of adenylyl cyclase. Here we used...

Proteintech Anti-DRD2 Polyclonal, Catalog # 55084-1-AP. Tested in Western Blot (WB), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (PFA fixed) (IHC (PFA)) and Immunoprecipitation (IP) applications. This antibody reacts with Human, Mouse, Rat samples. Supplied as 150 µL purified antibody (0.42 mg/mL).

2025年1月8日 · D2DR Antibody (B-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects D2DR of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked …

2023年10月1日 · Coimmunoprecipitation (Co-IP) results showed that H@P@M can also promote the internalization of DRD2 to form DRD2–ARRB1–USP8–Nrf2 protein complexes (Fig. 5 B). We further conducted IF and nuclear and cytoplasmic protein extraction experiments on Nrf2 and observed that H@P@M most effectively promoted Nrf2 expression and nuclear ...

D2DR抗体（B-10）是一种小鼠单克隆IgG2a kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、免疫组织化学和酶联免疫吸附测定（ELISA）检测小鼠、大鼠和人类来源的D2DR。

2015年8月6日 · Recently, dopamine D2 receptor (DRD2) is identified as an important component controlling innate immunity and inflammatory response in central nervous system, and αB-crystallin (CRYAB) is a potent negative regulator on inflammatory pathways.

Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using DRD2 antibody (55084-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). IP result of anti-DRD2 (IP:55084-1-AP, 4ug; Detection:55084-1-AP …