Protein kinase C - Wikipedia
In cell biology, protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through …
第二节 蛋白激酶C的信号传导通路和作用 - KKME
PKC信号通道是一条重要的细胞内信息传递通道，它存在于多种细胞内，通过催化蛋白质磷酸化反应、影响受体的上下调节、细胞膜和骨架的重塑及对转录的正负调节来调整细胞内某些特定的 …
蛋白激酶C - 百度百科
乙酸 豆塞外 佛波酯 （12-o-tertradecanoylphordol-13-acetate, TPA;或phorbol-12-myristate-13-acetate,PMA）是一种促 肿瘤 剂，由于基结构与DAG相似，可在很低浓度下模拟DAG，活 …
Diacylglycerol-evoked activation of PKC and PKD isoforms in …
2020年5月28日 · Protein kinase C (PKC) and Protein kinase D (PKD) isoforms can sense diacylglycerol (DAG) generated in the different cellular compartments in various physiological …
壹生资讯-糖尿病大血管病变发病机制——蛋白激酶C（PKC）途径
2021年1月31日 · dag是机体内主要的pkc激动剂。生理情况下，dag主要来源于磷酸肌醇的代谢和磷脂酰胆碱的裂解，但也可由脂质 前体 在磷脂酶a2的作用下释放出游离脂肪酸而生成。高血 …
PKC 通路 | Cell Signaling Technology
蛋白激酶 c (pkc) 家族成员调控大量的细胞反应，包括基因表达、蛋白分泌、细胞增殖和炎性反应。其基本的蛋白结构包括一个 n 端调节区，该调节区由一个铰链区连接至 c 端激酶区域。
PKD at the crossroads of DAG and PKC signaling - PubMed
DAG regulates the intracellular localization of PKD and also activates PKD through PKC by phosphorylation. The PKC-PKD signaling cascade is crucial to PKD function in cells. Important …
Protein kinase C and beyond - Nature Immunology
2004年7月28日 · DAG binds to conserved C1 domains in many different molecules, including various isoforms of PKC, PKD, Ras-GRP (activators of the GTPase Ras) and DGK (which …
Structural anatomy of Protein Kinase C C1 domain interactions …
2022年5月16日 · PKCs define a central DAG-sensing node in intracellular phosphoinositide signaling pathways that regulate cell growth, differentiation, apoptosis, and motility 9. Shortly …
PKD at the crossroads of DAG and PKC signaling - ScienceDirect
2006年6月1日 · Protein kinase D (PKD), a novel DAG receptor, has been the subject of intense investigation in recent years. DAG regulates the intracellular localization of PKD and also …