DBCO-NHS Ester | C23H18N2O5 | CID 77078178 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

DBCO-NHS Ester is a very popular amine-reactive click chemistry reagent. It can be used to modify an amine-containing molecule in organic solvents (limited solubility in aqueous media). It reacts with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds.

DBCO-NHS ester is commonly used in bioconjugation. It consists of an NHS ester that reacts with primary amines on biomolecules and an alkyne group that allows for a specific reaction with molecules containing azides.

DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition …

DBCO-NHS ester: An azido-reactive click-chemistry reagent. CAS Number: 1353016-71-3. Synonyms: DBCO N-hydroxysuccinimide ester, DIBAC N-hydroxysuccinimide ester, DIBAC-NHS ester, Dibenzocyclooctyne N-hydroxysuccinimide ester. Purity: ≥95%.

The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst. The ligation reaction is very fast and results in almost quantitative yield of stable triazoles.

DBCO-NHS is a copper-free click chemistry reagent for precise bioconjugation. It combines dibenzocyclooctyne (DBCO) with an NHS ester to enable stable, efficient reactions with azide-tagged molecules and primary amines, ideal for protein labeling and advanced research.

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain-promoted copper-free click chemistry (SPAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

DBCO-NHS Ester, also known as ADIBO-NHS Ester or DIBAC-NHS Ester, is an amine-reactive building block used for modification of amine-containing molecule in organic media. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds.

Aldrich-762040; Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester for Copper-free Click Chemistry; Synonyms: DBCO-sulfo-NHS ester; DBCO-sulfo-SE; Linear Formula: C25H21N2NaO8S; Empirical Formula: C25H21N2NaO8S; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich.

DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition …

DBCO (Dibenzocyclooctyne) is a cycloalkyne that can reacts with azides via strain-promoted 1,3-dipolar cycloaddition in aqueous solution, a bioorthogonal reaction also termed Cu-free click reaction.

Photocleavable DBCO-NHS ester reagent contains an amine reactive group linked to DBCO moiety through a spacer arm containing a photocleavable moiety. Molecules jointed by the copper-free click reaction can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW ...

• Mix antibody with 20-30 fold molar excess of DBCO NHS ester dissolved in DMSO (10 mM solution). DMSO content in the final mixture should be around 20%, antibody concentration in the reaction mixture around 1 mg/mL. • Incubate at room temperature for 60 minutes.

Within physiological temperature and pH ranges, the DBCO group will not react with thiol, amino or hydroxy groups that are naturally present in many biomolecules. DBCO NHS Ester is one of the most common reagents used for introducing DBCO group into a biomolecule via the modification of the amino groups.

DBCO-NHS Ester also known as ADIBO-NHS Ester or DIBAC-NHS Ester, is an amine-reactive building block used for modification of amine-containing molecule in organic media. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds.

DBCO-C6-NHS ester CAS# 1384870-47-6 Formula: C25H22N2O5 purity: ≥95%. 5000+ high purity PEG Linkers in stock. Support custom synthesis. Fast Shipping.

DBCO-C6-NHS ester is an amine-reactive compound, which can be used to modify an amine-containing molecule in organic media. This reagent isn't soluble in aqueous media.

DBCO-PEG4-NHS Ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond.

DBCO-Sulfo-NHS ester is a water-soluble sulfocated reagent containing DBCO moiety. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-bearing macromolecules with DBCO moiety in 100% aqueous buffers. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose.

Aldrich-764019; Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester ≥90%; Synonyms: DBCO-PEG4-NHS ester; DBCO-PEG4-SE; DBCO-PEG4-succinimidyl ester; Linear Formula: C34H39N3O10; Empirical Formula: C34H39N3O10; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich.

DBCO-S-S-NHS ester functions as a cleavable reagent containing NHS ester which can directly and efficiently react with amine-bearing molecules and DBCO which participates in copper-free Click Chemistry with azides. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME, and TCEP. Usually ships within 24 hours.