2024年12月24日 · DDB1 (Damage Specific DNA Binding Protein 1) is a Protein Coding gene. Diseases associated with DDB1 include White-Kernohan Syndrome and Xeroderma …

Damage-specific DNA binding protein 1 (DDB1) is a multifunctional protein that was first isolated as a subunit of a heterodimeric complex that recognises the UV-induced DNA lesions in the …

2023年11月22日 · Damage-specific DNA binding protein 1 (DDB1) is a component of the Cullin4A/B-RING E3 ubiquitin ligase (CRL4) complex and functions as an adaptor protein …

Results suggest that DDB1 prevents DNA lesions from accumulating in replicating human cells, in part by regulating Cdt1 degradation. the interaction with DDB1 mediates Vpr-induced …

DDB1-mediated CRY1 degradation promotes FOXO1 protein stability and FOXO1-mediated gluconeogenesis in the liver (By similarity). By acting on TET dioxygenses, essential for oocyte …

The DDB1 gene encodes damage-specific DNA-binding protein 1, which plays a vital role in the DNA damage response, specifically in the nucleotide excision repair pathway where it …

2021年4月1日 · The DNA damage-binding protein 1 (DDB1) is part of the CUL4-DDB1 ubiquitin E3 ligase complex (CRL4), which is essential for DNA repair, chromatin remodeling, DNA …

2025年1月5日 · Knockdown of damage-specific DNA binding protein 1 (DDB1) enhances the HBx-siRNA-mediated inhibition of HBV replication. Tang KF, Xie J, Chen M, Liu Q, Zhou XY, …

DDB1, a component of a Cul4A ubiquitin ligase complex, promotes nucleotide excision repair (NER) and regulates DNA replication. We have investigated the role of human DDB1 in …

2011年12月1日 · Damage-specific DNA binding protein 1 (DDB1) is a conserved protein that is involved in the nucleotide excision repair pathway (NER) as a component of the damaged …