Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked …
2023年11月22日 · Damage-specific DNA binding protein 1 (DDB1) is a component of the Cullin4A/B-RING E3 ubiquitin ligase (CRL4) complex and functions as an adaptor protein …
DDB1 - Wikipedia
As its name suggests, DDB1 was initially implicated in the process of a specific type of DNA repair known as nucleotide excision repair. Since then, researchers have found that DDB1 primarily …
Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with ...
2014年7月16日 · IMiDs target the E3 ubiquitin ligase CUL4–RBX1–DDB1–CRBN (known as CRL4 CRBN) and promote the ubiquitination of the IKAROS family transcription factors IKZF1 …
Damage-specific DNA binding protein 1 (DDB1): a protein with a …
2011年12月1日 · CUL4–DDB1 E3–ligase complex regulates the selective proteolysis of key proteins in DNA repair, replication and transcription. In addition, DDB1 plays a role in …
Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with ...
2014年8月7日 · IMiDs target the E3 ubiquitin ligase CUL4-RBX1-DDB1-CRBN (known as CRL4 (CRBN)) and promote the ubiquitination of the IKAROS family transcription factors IKZF1 and …
DDB1-CRBN E3 泛素连接酶与沙利度胺复合物的结构,Nature - X …
2014年7月16日 · IMiDs target the E3 ubiquitin ligase CUL4–RBX1–DDB1–CRBN (known as CRL4CRBN) and promote the ubiquitination of the IKAROS family transcription factors IKZF1 …
DDB1 Gene - GeneCards | DDB1 Protein | DDB1 Antibody
2024年12月24日 · DDB1 (Damage Specific DNA Binding Protein 1) is a Protein Coding gene. Diseases associated with DDB1 include White-Kernohan Syndrome and Xeroderma …
人类 Cereblon-DDB1-来那度胺复合物的结构揭示了对沙利度胺类 …
这些药物直接结合 Cereblon (CRBN) 并促进底物 Ikaros (IKZF1) 和 Aiolos (IKZF3) 向 E3 复合物的募集，从而导致底物泛素化和降解。 在这里，我们展示了与 DDB1 和药物来那度胺结合的人 …
Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 …
The human DDB1-CUL4 ASSOCIATED FACTOR (DCAF) proteins have been reported to interact directly with UV-DAMAGED DNA BINDING PROTEIN1 (DDB1) through the WDxR motif in …
与细胞周期调节相关的 DDB1-AMBRA1 E3 连接酶受体复合物的结 …
The HDX results indicated that AMBRA1 is a highly flexible protein and can be stabilized upon interaction with DDB1, the adaptor of the Cullin4A/B E3 ligase. Here, we present the cryo-EM …