Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked …
2023年11月22日 · Damage-specific DNA binding protein 1 (DDB1) is a component of the Cullin4A/B-RING E3 ubiquitin ligase (CRL4) complex and functions as an adaptor protein …
DDB1 - Wikipedia
DDB1 contains 1140 amino acids, amounting to a mass of 127 kDa. [8] As its name suggests, DDB1 was initially implicated in the process of a specific type of DNA repair known as …
Damage-specific DNA binding protein 1 (DDB1): a protein with a …
2011年12月1日 · DDB1 interacts with the Fmod and MMP-13 promoters and may function as a transcriptional partner of E2F1. DDB1 targets the replication licensing protein (Cdt1) for …
Q16531 - UniProt
The DDB1-CUL4A-DTL E3 ligase complex regulates the circadian clock function by mediating the ubiquitination and degradation of CRY1 (PubMed:26431207). DDB1-mediated CRY1 …
DDB1 Gene - GeneCards | DDB1 Protein | DDB1 Antibody
2024年12月24日 · DDB1 (Damage Specific DNA Binding Protein 1) is a Protein Coding gene. Diseases associated with DDB1 include White-Kernohan Syndrome and Xeroderma …
Damage-specific DNA binding protein 1 (DDB1): a protein with a …
Damage-specific DNA binding protein 1 (DDB1) is a multifunctional protein that was first isolated as a subunit of a heterodimeric complex that recognises the UV-induced DNA lesions in the …
Entry - *600045 - DNA DAMAGE-BINDING PROTEIN 1; DDB1
The DDB1 gene encodes damage-specific DNA-binding protein 1, which plays a vital role in the DNA damage response, specifically in the nucleotide excision repair pathway where it …
损伤特异性 DNA 结合蛋白 1（DDB1）基因 | MCE
由该基因编码的蛋白质是异二聚体 DNA 损伤结合 (DDB) 复合物的大亚基 (p127) ，而另一种蛋白质 (p48) 形成小亚基。 这种蛋白质复合物在核苷酸切除修复中起作用，并在紫外线损伤后与 DNA …
Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with ...
2014年7月16日 · IMiDs target the E3 ubiquitin ligase CUL4–RBX1–DDB1–CRBN (known as CRL4 CRBN) and promote the ubiquitination of the IKAROS family transcription factors IKZF1 …
赵同金教授团队揭示DDB1在调控脂肪组织发育和肥胖发生中的生理作用
DDB1 (Damage-specific DNA binding protein 1) 是一种多功能蛋白，最早是作为紫外诱导复合物（与DDB2形成异源二聚体）中的一个组分被发现的。 目前，DDB1被广泛认为是Cullin …