
Neurological aspects of del (1q) syndrome - PubMed
1991年9月15日 · We have studied three children with de novo terminal deletion of the long arm of chromosome 1 (46,XX,del (1) (q43)). They all have minor anomalies and neurological signs …
Gain of Chromosome 1q is associated with early progression in …
2019年11月25日 · Gain of chromosome 1q (+1q) is commonly identified in multiple myeloma and has been associated with inferior outcomes. However, the prognostic implication of +1q has …
1q translocations (unbalanced) in myeloid malignancies
2013年5月1日 · The balanced translocation t (1;1) (p36;q21) involving the DUSP10 / PRDM16 genes is associated with myeloid disorders; the unbalanced der (1)t (1;1) involving 1q11-32 …
Chromosomal 1q21 abnormalities in multiple myeloma: a …
Gain or amplification of 1q21 (1q21+) occurs in around 40% of patients with MM and generally portends a poor prognosis. Patients with MM who harbor 1q21+ are at increased risk of drug …
1q21.1 Recurrent Deletion - GeneReviews® - NCBI Bookshelf
2011年2月24日 · Chromosomal microarray (CMA) using oligonucleotide arrays or SNP genotyping arrays can detect the common deletion in a proband. The ability to size the …
Molecular characterization of a patient with an interstitial 1q ...
2008年10月27日 · Here we report on a patient with an interstitial deletion on the long (q) arm of chromosome 1 who presents with a unique constellation of anomalies including brachydactyly …
DEL-1 promotes macrophage efferocytosis and clearance of ... - PubMed
Here we found that developmental endothelial locus-1 (DEL-1), a secreted protein that inhibits leukocyte-endothelial adhesion and inflammation initiation, also functions as a non-redundant …
Blood:多发性骨髓瘤治疗迈入“精准”时代——分子生物学检测指 …
del(1p)(诊断时发生率10%) 经常与gain(1q) 共存,与自体 干细胞 移植患者不良结果相关,可能与1p32位点上的CDKN2C和FAF1、1p12位点上的FAM46C、1p22位点上的RPL5 …
Making a case for del (1p) as a high‐risk abnormality in multiple ...
2023年6月6日 · In this retrospective study, the authors found that del (1p13.3) is associated with inferior progression-free survival (PFS) and overall survival (OS) compared to patients without …
Neurological aspects of del (1q) syndrome - Academia.edu
We have evaluated three children with del (1q) syndrome with special interest in their neurological problems. All of these patients had similar autistic-like behavior and unusual phonations that …
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