1991年9月15日 · We have studied three children with de novo terminal deletion of the long arm of chromosome 1 (46,XX,del (1) (q43)). They all have minor anomalies and neurological signs …

2019年11月25日 · Gain of chromosome 1q (+1q) is commonly identified in multiple myeloma and has been associated with inferior outcomes. However, the prognostic implication of +1q has …

2013年5月1日 · The balanced translocation t (1;1) (p36;q21) involving the DUSP10 / PRDM16 genes is associated with myeloid disorders; the unbalanced der (1)t (1;1) involving 1q11-32 …

Gain or amplification of 1q21 (1q21+) occurs in around 40% of patients with MM and generally portends a poor prognosis. Patients with MM who harbor 1q21+ are at increased risk of drug …

2011年2月24日 · Chromosomal microarray (CMA) using oligonucleotide arrays or SNP genotyping arrays can detect the common deletion in a proband. The ability to size the …

2008年10月27日 · Here we report on a patient with an interstitial deletion on the long (q) arm of chromosome 1 who presents with a unique constellation of anomalies including brachydactyly …

Here we found that developmental endothelial locus-1 (DEL-1), a secreted protein that inhibits leukocyte-endothelial adhesion and inflammation initiation, also functions as a non-redundant …

del（1p）（诊断时发生率10%） 经常与gain（1q） 共存，与自体 干细胞 移植患者不良结果相关，可能与1p32位点上的CDKN2C和FAF1、1p12位点上的FAM46C、1p22位点上的RPL5 …

2023年6月6日 · In this retrospective study, the authors found that del (1p13.3) is associated with inferior progression-free survival (PFS) and overall survival (OS) compared to patients without …

We have evaluated three children with del (1q) syndrome with special interest in their neurological problems. All of these patients had similar autistic-like behavior and unusual phonations that …