Dillenia indica L. attenuates diabetic nephropathy via inhibition …
2018年1月1日 · STZ-injection produced dyslipidemia in the form of elevated serum TC, TG level, LDL, VLDL and reduced HDL level in diabetic control group compared to normal control rats. …
Nox4-SH3YL1 complex is involved in diabetic nephropathy - Cell …
2024年2月16日 · Here, we report the function of SH3YL1 as a novel regulator of Nox4 in streptozotocin (STZ)-induced type Ⅰ diabetes as a DN model and present a downstream …
Pyruvate dehydrogenase kinase 1 protects against neuronal injury …
2023年11月7日 · Enhancing PDK1 expression in the hippocampus ameliorated STZ-induced cognitive impairment and neuronal degeneration in mice. Together, our study demonstrated …
Dihydrolipoamide S-acetyltransferase activation alleviates diabetic ...
2024年12月1日 · Diabetic kidney disease (DKD), a severe complication of diabetes marked by deregulated glucose metabolism, remains enigmatic in its pathogenesis. Herein, we delved …
Hexarelin Protects Rodent Pancreatic Β-Cells Function from ... - PLOS
2016年2月26日 · Rhodamine 123 assay and superoxide DHE production assay revealed that Hex ameliorated STZ-induced mitochondrial damage and excessive superoxide activity in β-cells. …
2020年11月18日 · OGG1 and AMPK levels were measured after metformin treatment while HG-caused ROS was measured by DHE prober. Diabetic mice were induced by daily …
The effects of heavy long-term exercise on ventricular myocyte ...
2010年7月1日 · The effects of a heavy exercise training program on shortening and intracellular Ca 2+ in unloaded ventricular myocytes from streptozotocin (STZ)-induced diabetic rats were …
Effect of DAE and DHE on Lipid Profile in diabetic ... - ResearchGate
The impact of STZ-induced DNP was analyzed through the estimation of body weight, serum glucose, and hemoglobin A1c levels, renal functional parameters, the serum lipid profile, …
p66Shc regulates podocyte autophagy in high glucose
DHE/ET fluorescence quantification was used for ROS detection and quantification. Results: Urine creatinine, serum creatinine, urinary microalbumin, and p66Shc expression were …
Neural Degeneration in the Retina of the Streptozotocin-Induced …
2011年11月17日 · Oxidative stress in the retina of the STZ-induced diabetes model mouse. Dihydroethidium (DHE) indicates ROS in the retina (a). The level of diabetes-induced ROS in …