Nucleic DHX9 cooperates with STAT1 to transcribe interferon
2023年2月3日 · We found that pY701-STAT1 levels were comparable in BMDMs from Dhx9 f/f LysM-Cre and Dhx9 f/f mice after IFN-β stimulation (fig. S8). DHX9 has been extensively …
RNA damage compartmentalization by DHX9 stress granules
2024年3月18日 · Here, we identified a distinct stress granule (SG), marked by dsRNA helicase DHX9, which compartmentalizes ultraviolet (UV)-induced RNA, but not DNA, damage. Our …
DExD/H-box helicase 9 intrinsically controls CD8 - Science
2022年2月9日 · We found that T cell–specific deletion of nuclear helicase Dhx9 led to impaired CD8 + T cell survival, effector differentiation, and viral clearance. Mechanistically, Dhx9 acts …
Monoallelic variation in DHX9, the gene encoding the DExH-box …
2023年8月3日 · DHX9 encodes a BRCA1-interacting nuclear helicase regulating transcription, R-loops, and homologous recombination and exhibits the highest mutational constraint of all …
A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates ...
2025年2月17日 · In this report, we show that DHX9 knockdown increased RNA/DNA secondary structures and replication stress, resulting in cell-cycle arrest and the onset of apoptosis in …
USP42 enhances homologous recombination repair by promoting …
2020年6月15日 · Consistently, pRPA2 S4/S8 signal induced by CPT treatment was disturbed by depleting endogenous DHX9 (data not shown), which tended to be rescued by transient over …
Science Advances | 中国科学技术大学朱书等团队合作揭示了DHX9 …
2023年2月9日 · dhx9是一种多功能核蛋白，目前尚不清楚它是否在调节细胞核中针对rna病毒的先天免疫中发挥作用。 这项研究表明，DHX9与体内针对RNA病毒感染的先天免疫应答密切相关。
Fig. S8 Motifs discovery and analysis within the 5'-UTR of DHX9 …
RNA helicase A/DHX9 (DExH-box helicase 9) binds to and resolves both G4-DNA and G4-RNA and promotes translation by unwinding 5′-UTR G4-RNA structures (Chakraborty and Grosse, …
Monoallelic variation in DHX9, the gene encoding the DExH-box …
2023年8月3日 · DHX9 encodes a BRCA1-interacting nuclear helicase regulating transcription, R-loops, and homologous recombination and exhibits the highest mutational constraint of all …
Single-cell transcriptomics reveal DHX9 in mature B cell as a …
2021年9月24日 · We finally obtained DEAH-box helicase 9 (DHX9), a key DNB gene, as a biomarker in adjacent tissues B cells that is indicative of pre-metastasis before lymph node …