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Diabetic vascular diseases: molecular mechanisms and therapeutic ...
2023年4月10日 · Diabetic panvascular disease (DPD) is a clinical syndrome in which vessels of various sizes, including macrovessels and microvessels in the cardiac, cerebral, renal, ophthalmic, and...
Mechanisms of diabetic vasculopathy: an overview - Oxford …
2001年5月1日 · Vascular complications remain the major cause of morbidity and mortality in the diabetic population. 1 Diabetes provides a distinct model of chronic vascular disease in which altered glucose homeostasis eventuates in multiorgan dysfunction. These complications can be divided into microvascular and macrovascular complications.
Diabetic Vasculopathy: Molecular Mechanisms and Clinical Insights
The present review focuses on the relationship between insulin resistance and diabetes mellitus in diabetic vasculopathy and related cardiovascular disease, highlighting epidemiology and clinical characteristics, pathophysiology, and molecular mechanisms, as well as management strategies.
Diabetes and Vascular Disease | Circulation - AHA/ASA Journals
2003年9月23日 · It is likely that the incidence of type 2 diabetes will rise as a consequence of lifestyle patterns contributing to obesity. 2 Cardiovascular physicians are encountering many of these patients because vascular diseases are the principal causes of death and disability in people with diabetes.
Diabetic vasculopathy: macro and microvascular injury
This review aims to showcase the evolution and effects of diabetic vasculopathy from development to clinical disease as macrovascular and microvascular complications with a concerted reference to sex-specific disease progression as well.
Diabetic vascular diseases: molecular mechanisms and therapeutic ...
Diabetic panvascular disease (DPD) is a clinical syndrome in which vessels of various sizes, including macrovessels and microvessels in the cardiac, cerebral, renal, ophthalmic, and peripheral systems of patients with diabetes, develop atherosclerosis as a common pathology.
Diabetic Vasculopathy: Molecular Mechanisms and Clinical …
2024年1月9日 · The present review focuses on the relationship between insulin resistance and diabetes mellitus in diabetic vasculopathy and related cardiovascular disease, highlighting epidemiology and clinical characteristics, pathophysiology, and molecular mechanisms, as well as management strategies.
Evolution and diabetic vasculopathy - PMC - National Center for ...
2022年6月9日 · Diabetic vasculopathy only develops in mammals, whereas diabetes‐like conditions are observed among a wide range of species. One may ask; how such diversity has emerged? One answer can be it is the result of evolution.
Diabetes and peripheral artery disease: A review - PMC
Diabetes mellitus (DM) remains a major risk for PAD, with DM patients having more than two-fold increased prevalence of PAD compared with the general population. The clinical presentation in people with DM also differs slightly from that in the general population.
Diabetes and vascular disease: pathophysiology, clinical …
2013年5月2日 · The alterations in vascular homeostasis due to endothelial and smooth muscle cell dysfunction are the main features of diabetic vasculopathy favouring a pro-inflammatory/thrombotic state which ultimately leads to atherothrombosis.