We have read with great interest the analysis by Meczker et al1 reporting on 1060 patients with drug-induced acute pancreatitis (DIAP). The authors meticulously collected data from worldwide published case reports and case series of DIAP and compared them with a Hungarian cohort of 1225 patients with acute pancreatitis of any cause.

2020年2月20日 · We aimed to systematically search the medical literature, analyze the outcomes of all reported cases of DIAP, and compare them against a general cohort of AP. We comprehensively searched the literature for reported cases of proven DIAP and extracted detailed data of each case on both first episodes and rechallenges.

Drug-induced acute pancreatitis (DIAP) is a rare entity that is often challenging for clinicians. The aim of our study was to provide updated DIAP classes considering the updated definition of acute pancreatitis (AP) and in light of new medications and new case reports.

2020年9月1日 · Drug induced acute pancreatitis (DIAP) as one of the acute pancreatitis (AP) risks factors is a poorly understood entity. The aim of the current study was to compare the characteristics and course of DIAP cases in children presenting with a first attack of AP.

2020年10月1日 · Our study showed a prevalence of DIAP of (3.6%) and hydrochlorothiazide, azathioprine, and doxycycline were the most common culprit drugs. Acute pancreatitis (AP) is an inflammatory condition of the pancreas. Annually, it accounts for up to 275,000 hospitalizations in the United States [1].

Acute pancreatitis (AP) is an acute inflammation of the pancreas caused by the activation of digestive enzymes in the pancreatic tissue. The main causes of AP are cholelithiasis and alcohol abuse; less commonly, it can be caused by drugs, with a prevalence of up to 5%.

急性胰腺炎 (acute pancreatitis，AP)是由各种病因引起胰酶激活导致的胰腺局部炎症反应，伴或不伴其他器官功能障碍。 根据2012年亚特兰大标准，AP分为轻症、中度重症和重症AP [1]。 大多数AP患者为轻症，病程呈自限性，但重症患者的死亡率较高 (15%~30%)，对AP病因进行早期诊断和治疗有助于缓解病情、改善预后并减少胰腺炎复发。 胆石症 (40%~70%)和摄入乙醇 (25%~35%)是AP的常见病因，胰腺肿瘤、感染、药物、高钙血症、自身免疫病、血液透析相关性胰腺炎、 …

pancreatitis (AP) has a mortality of approxi-mately 3%.1 Its reported incidence is variable across countries (10 to 100/100,000 inhabitants), and in the United States, AP is a significant cause of acute hospi-talization for gastrointestinal disorders.2Drug-induced AP (DIAP) is regarded as a rare and mild entity; yet, it is esti-mated to account ...

Hypertriglyceridemia-associated DIAP is a rare phenomenon, and the current systematic review provides a summary of drugs that have been implicated in this phenomenon, which allow physicians to be oriented about this adverse effect when these drugs are used.

2020年9月1日 · DIAP is a leading risk factor for a first attack of AP in children and is associated with increased morbidity and severity of the pancreatitis course. DIAP warrants further investigation in future studies.