2025年2月17日 · Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma. Diffuse large B-cell lymphoma is sometimes associated with immunodeficiency, including acquired immunodeficiency syndrome (AIDS).

2023年4月24日 · Diffuse large B cell lymphoma (DLBCL) is the most common lymphoma, accounting for about 25% to 30% of all the non-Hodgkin lymphomas. It typically presents as a rapidly growing mass or enlarging lymph nodes in a nodal or extranodal site.

2021年12月13日 · 弥漫大B细胞淋巴瘤（DLBCL）是成人非霍奇金淋巴瘤最常见的类型，约占30-40％，亚洲国家多大于40%。 DLBCL是一组大细胞、侵袭性的恶性淋巴瘤，中位发病年龄65岁，超过一半的DLBLC患者可以使用标准的R-CHOP方案治愈，但大约30％至40％的患者会发展为复发/难治性肿瘤。 DLBCL可原发于淋巴结或胃肠道、中枢神经系统、皮肤、纵膈和骨骼等几乎全身各个部位。 DLBCL也可从惰性淋巴瘤转化而来，比如慢性淋巴细胞性白血病/小淋巴细胞性淋 …

2013年7月4日 · We investigated whether positron emission tomography combined with computed tomography (PET-CT) identifies clinically important bone marrow involvement by diffuse large B-cell lymphoma (DLBCL) with sufficient accuracy to replace routine staging bone marrow biopsy.

2016年10月8日 · Diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma can present with peritoneal lymphomatosis in rare cases. Diagnosis cannot be obtained solely by history, physical examination, imaging, and cytology. Biopsy of masses via CT guided imaging and/or laparoscopy can be beneficial in properly diagnosing non-Hodgkin lymphoma.

The value of interim ¹⁸F-FDG PET/CT (iPET)-guided treatment decisions in patients with diffuse large B-cell lymphoma (DLBCL) has been the subject of much debate. This investigation focuses on a comparison of the Deauville score and the change-in-SUV_max (ΔSUV_max) appr …

循环肿瘤DNA（Circulating Tumor DNA，ctDNA）检测是DLBCL临床诊疗中的重要方法，在分子分型、风险预测、用药指导、动态监测以及预后评估等方面起重要作用。 本期将通过几篇代表性临床研究，基于ctDNA不同 技术平台，系统性地介绍其在DLBCL治疗中的应用场景。 1.液体活检用于弥漫性大B细胞淋巴瘤突变图谱和克隆进化研究. 背景： 受限于临床肿瘤活检组织获取困难，在DLBCL患者治疗时通过基因检测结果进行预后和疗效评估不易，且常规在耐药之后取一系列 …

2025年3月18日 · Diffuse large B-cell lymphoma (DLBCL) is the most prevalent form of lymphoma. The overexpression of CtBP2 in tissues may contribute to tumor occurrence and progression. The expression of EGR1 in DLBCL is elevated, suggesting its potential role as an oncogene that promotes the proliferation of DLBCL …

CT is particularly useful for anatomical delineation of pathological lymph nodes and extranodal disease, for guiding biopsies of deep seated lymph nodes, particularly in the mediastinum or retroperitoneum, and in formulating treatment plans. MRI is useful in imaging central and peripheral nervous system involvement.

Our results confirm that CT could be considered as first line therapy for newly diagnosed gastric DLBC lymphoma; IF RT delivered in those patients achieving CR after induction CT is able to prevent local relapse.