2024年4月1日 · Easy-to-read patient leaflet for Dornase Alfa. Includes indications, proper use, special instructions, precautions, and possible side effects.

Dornase alfa, sold under the brand name Pulmozyme, is used for the treatment of cystic fibrosis. [3] It is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. [3] Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions. [3]

2024年1月31日 · Dornase alfa inhalation solution is used together with other medicines (eg, antibiotics, bronchodilators, and steroids) to control symptoms of cystic fibrosis. Cystic fibrosis is a condition in which a thick mucus is formed in the lungs and breathing passages.

Dornase alfa is an inhaled medication that thins mucus, used to manage and treat cystic fibrosis. It has been shown to decrease respiratory tract infections in selected patients with forced vital capacity (FVC) greater than 40% of predicted.

Pulmozyme® (dornase alfa) is a nebulized cystic fibrosis (CF) treatment option to help manage CF symptoms. See full safety for more information.

Dornase alfa is used to reduce the number of lung infections and to improve lung function in patients with cystic fibrosis. It breaks down the thick secretions in the airways, allowing air to flow better and preventing bacteria from building up.

2005年6月13日 · Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme.

2024年6月28日 · What is dornase alfa? Dornase alfa is used in people with cystic fibrosis to thin mucus in the airways. This may help improve lung function and lower the risk of infections. Dornase alfa may also be used for purposes not listed in this medication guide.

2024年7月30日 · Generic name: dornase alfa (inhalation) [ DOOR-nase-AL-fa ] Drug class: Miscellaneous respiratory agents. Medically reviewed by Philip Thornton, DipPharm. Last updated on Jul 30, 2024. Uses; Warnings; Before taking; Dosage; Side …

What is this drug used for? It is used to lower the number of lung infections and help lung function in cystic fibrosis. What do I need to tell my doctor BEFORE I take this drug? If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.