Death receptor 5 (DR5), also known as TRAIL receptor 2 (TRAILR2) and tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), is a cell surface receptor of the TNF-receptor superfamily that binds TRAIL and mediates apoptosis.

2020年9月1日 · DR5 is an artificially synthesized and highly active auxin-response element that contains seven tandem direct repeats of 11 bp, including the auxin responsive factor gene-binding site (TGTCTC) (Ulmasov et al., 1997).

2013年1月3日 · DR5 activity was highest in cortex, suggesting high levels of auxin concentration and/or sensitivity in this tissue. Our study shows that the DR5 reporter system is a sensitive and facile system for monitoring auxin responses and distribution at cellular resolution in poplar.

2024年1月10日 · DR5 gene deletion caused apoptosis and DNA damage in transit amplifying cells by inhibiting ERK1/2 activity in intestinal crypts. Inhibition of ERK1/2 with PD0325901 dampened the ISC activity and...

a transcript encoding the death receptor DR5 originates from an ERV9-LTR inserted upstream of the protein coding regions of the TNFRSF10B gene, and it shows an expression pattern similar to GTAp63

2019年1月10日 · Here, we discuss regulation of DR5 expression or activation by epigenetic modification, transcription factor at the transcriptional levels, micro RNA and RNA-binding proteins at the post-transcriptional levels, and ubiquitination and glycosylation at …

Death Receptor 5 (DR5) is expressed on the surface of primary bone and soft tissue sarcoma cells, and its activation induces cell death primarily through apoptosis. The combination of DR5 agonists and commonly used chemotherapeutic agents, such as …

Our study shows that the DR5 reporter system is a sensitive and facile system for monitoring auxin responses and distribution at cellular resolution in poplar. Auxin-responsive DR5 promoter coupled with transport assays suggest separate but linked routes of auxin transport during woody stem development in Populus.

2024年12月24日 · DRD5 (Dopamine Receptor D5) is a Protein Coding gene. Diseases associated with DRD5 include Blepharospasm, Benign Essential and Attention Deficit-Hyperactivity Disorder. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling.

DR5是一种生长素特异性启动子，已被报道为监测不同物种和器官中生长素表达和分布的有效工具。 E8启动子作为应用最广泛的水果特异性启动子之一，广泛用于成熟番茄果实的特异性表达。