2025年1月18日 · A comprehensive list of conditions and drugs that may prolong the QT interval, and cause torsade de pointes (TdP) and long QT syndrome (LQTS) is presented below. With regards to drugs, the risk of QT prolongation and TdP varies markedly across the list but tends to be rather similar within a drug class.

QT prolongation is an established side effect of antiarrhythmics, but can also be caused by a wide range of non-cardiac medicines, including antibiotics, antidepressants, antihistamines, opioids, and complementary medicines.

2007年2月20日 · Drugs that have QT-prolonging effects should not exceed recommended dosing range, as drug-induced arrhythmia is often a result of high drug concentrations. In addition, these medications should be prescribed with caution in patients who have underlying risk factors, such as cardiac disorders.

2024年8月16日 · QT prolongation is a rare medication side effect that can cause your heart to beat abnormally. Notable QT-prolonging drugs include antiarrhythmics, such as amiodarone (Pacerone), and antipsychotics, such as chlorpromazine and ziprasidone (Geodon).

2024年10月8日 · Drugs associated with QT Prolongation, QTc prolongation including Antipsychotics, antiarrhythmics, antidepressants, and antihistamines

Prolongation of the QT interval can lead to a life threatening arrhythmia known as torsades de pointes. Over the last few years a number of warnings have highlighted the risk of QT prolongation with citalopram, domperidone, ondansetron, hydroxyzine and quinine.

2023年6月17日 · Prolongation of the QT interval can lead to a life threatening ventricular arrhythmia known as torsades de pointes which can result in sudden cardiac death. The risk of torsades de pointes depends on patient factors and current medication.

are a number of widely used drugs which are known to cause QT prolongation. The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a number of warnings relating to drug-induced QT prolongation for some commonly used drugs – e.g.

When doctors prescribe a drug with an IKr blocking activity, or any other QT prolonging action, to patients affected by the long QT syndrome they are in essence presenting them with a potential time bomb which may, or may not explode in a near or distant future.

QT-interval–prolonging antiarrhythmic agents such as sotalol, dofetilide, and ibutilide can prolong the QT interval by more than 50 msec at clinically pre-scribed doses and may cause...