Down syndrome regression disorder (DSRD), also referred to as regression, is a rare but serious disorder that occurs in some adolescents and young adults with Down syndrome. Regression is used to describe the loss of skills an individual has previously learned.

Down syndrome regression disorder (DSRD) is a rare condition involving subacute cognitive decline, loss of previously acquired developmental skills, and prominent neuropsychiatric symptoms, particularly catatonia, in people with Down syndrome. It is thought to involve both autoimmune and neuropsychiatric mechanisms.

2023年3月1日 · This review highlights recent advances in the diagnosis and clinical approach to DSRD and reviews the most up-to-date literature on therapeutic interventions for this condition.

2024年4月15日 · Down Syndrome Regression Disorder (DSRD) is a perplexing condition that manifests as a significant loss of skills and abilities in individuals with Down syndrome (DS). While the exact mechanisms underlying DSRD remain elusive, emerging research suggests that neuroimmunology factors may play a pivotal role in its pathogenesis.

2022年7月15日 · The authors present international consensus agreement on the nomenclature, diagnostic work up, and diagnostic criteria for DSRD, providing an initial practical framework that can advance both research and clinical practices for this condition.

2023年1月10日 · Children’s Hospital Los Angeles has launched the first clinical trial for Down syndrome regression disorder (DSRD), a rare and debilitating condition that affects adolescents and young adults with Down syndrome.

Down Syndrome Regression Disorder (DSRD), sometimes also referred to as just regression, is a disorder that occurs in some adolescents and young adults with Down syndrome. It is a serious disorder wherein the individual loses skills they had previously learned such as daily living, language, movement, or social skills.

2023年8月7日 · That’s how families describe their experience with Down syndrome regression disorder (DSRD)—a rare condition that causes previously high-functioning young people with Down syndrome to suddenly lose their ability to communicate, dress or feed themselves, use the bathroom or even sleep.

One of the causes of regression is a specific disorder that is referred to as Down syndrome regression disorder (DSRD), Down syndrome disintegrative disorder (DSDD) or unexplained regression in Down syndrome (URDS) and these terms are sometimes used interchangeably. In this document, we will use ‘Down syndrome regression disorder’ (DSRD)’.

Individuals with Down syndrome (DS) have an increased risk of numerous co-occurring conditions, including the rare neurological condition known as Down Syndrome Regression Disorder (DSRD). Individuals with a DSRD diagnosis often experience symptoms like catatonia or unresponsiveness, loss of speech, loss of ability to perform activities of ...